Detalhe da pesquisa
1.
Triazinium Ligation: Bioorthogonal Reaction of N1-Alkyl 1,2,4-Triazinium Salts.
Angew Chem Int Ed Engl
; 62(36): e202306828, 2023 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37436086
2.
Structural Analysis of the OC43 Coronavirus 2'-O-RNA Methyltransferase.
J Virol
; 95(15): e0046321, 2021 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34011548
3.
Cell-autonomous hepatocyte-specific GP130 signaling is sufficient to trigger a robust innate immune response in mice.
J Hepatol
; 74(2): 407-418, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32987028
4.
KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype.
PLoS Genet
; 13(1): e1006566, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28095415
5.
Plectin controls biliary tree architecture and stability in cholestasis.
J Hepatol
; 68(5): 1006-1017, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29273475
6.
Structural and functional insights in flavivirus NS5 proteins gained by the structure of Ntaya virus polymerase and methyltransferase.
Structure
; 2024 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38781970
7.
Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function.
Structure
; 32(4): 433-439.e4, 2024 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38325369
8.
Liver protective effect of ursodeoxycholic acid includes regulation of ADAM17 activity.
BMC Gastroenterol
; 13: 155, 2013 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-24172289
9.
Sulfonothioated meso-Methyl BODIPY Shows Enhanced Uncaging Efficiency and Releases H2Sn.
Org Lett
; 25(36): 6705-6709, 2023 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37668439
10.
Discovery and structural characterization of monkeypox virus methyltransferase VP39 inhibitors reveal similarities to SARS-CoV-2 nsp14 methyltransferase.
Nat Commun
; 14(1): 2259, 2023 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37080993
11.
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure.
J Med Chem
; 66(4): 2422-2456, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36756805
12.
Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors.
ACS Omega
; 8(30): 27410-27418, 2023 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37546609
13.
Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-b]pyridazine Derivatives Identified by Scaffold Hopping.
J Med Chem
; 66(16): 11133-11157, 2023 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37535845
14.
Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors.
J Med Chem
; 66(10): 6652-6681, 2023 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37134237
15.
Off-target lipid metabolism disruption by the mouse constitutive androstane receptor ligand TCPOBOP in humanized mice.
Biochem Pharmacol
; 197: 114905, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34971590
16.
ADAM10 and ADAM17 regulate EGFR, c-Met and TNF RI signalling in liver regeneration and fibrosis.
Sci Rep
; 11(1): 11414, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34075077
17.
Localization of SARS-CoV-2 Capping Enzymes Revealed by an Antibody against the nsp10 Subunit.
Viruses
; 13(8)2021 07 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34452352
18.
Discovery of Modified Amidate (ProTide) Prodrugs of Tenofovir with Enhanced Antiviral Properties.
J Med Chem
; 64(22): 16425-16449, 2021 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34713696
19.
The Effect of Mycotoxins and Silymarin on Liver Lipidome of Mice with Non-Alcoholic Fatty Liver Disease.
Biomolecules
; 11(11)2021 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34827721
20.
Vegan Diet Is Associated With Favorable Effects on the Metabolic Performance of Intestinal Microbiota: A Cross-Sectional Multi-Omics Study.
Front Nutr
; 8: 783302, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35071294