Detalhe da pesquisa
1.
An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED.
Nat Chem Biol
; 13(4): 381-388, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28135235
2.
Histone methylation by PRC2 is inhibited by active chromatin marks.
Mol Cell
; 42(3): 330-41, 2011 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21549310
3.
Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation.
Proc Natl Acad Sci U S A
; 109(52): 21360-5, 2012 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23236167
4.
Direct quantification of circulating miRNAs in different stages of nasopharyngeal cancerous serum samples in single molecule level with total internal reflection fluorescence microscopy.
Anal Chem
; 86(19): 9880-6, 2014 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25207668
5.
Monitoring of DNA-protein interaction with single gold nanoparticles by localized scattering plasmon resonance spectroscopy.
Methods
; 64(3): 331-7, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23954570
6.
Multifunctional encoded self-assembling protein nanofibrils as platform for high-throughput and multiplexed detection of biomolecules.
Anal Chem
; 83(24): 9370-7, 2011 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22040164
7.
Direct quantification of single-molecules of microRNA by total internal reflection fluorescence microscopy.
Anal Chem
; 82(16): 6911-8, 2010 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20704380
8.
Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer.
J Med Chem
; 63(22): 13578-13594, 2020 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32910655
9.
6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors.
J Med Chem
; 62(4): 1793-1802, 2019 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30688459
10.
Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors.
J Med Chem
; 62(4): 1781-1792, 2019 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30688462
11.
E2F-dependent histone acetylation and recruitment of the Tip60 acetyltransferase complex to chromatin in late G1.
Mol Cell Biol
; 24(10): 4546-56, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15121871
12.
A chemical genetics approach for the functional assessment of novel cancer genes.
Cancer Res
; 75(10): 1949-58, 2015 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25788694
13.
Self-assembling protein platform for direct quantification of circulating microRNAs in serum with total internal reflection fluorescence microscopy.
Anal Chim Acta
; 823: 61-8, 2014 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24746354
14.
Correction to Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors.
J Med Chem
; 62(7): 3780, 2019 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30900881
15.
Correction to 6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors.
J Med Chem
; 62(7): 3781, 2019 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30900883
16.
N-Acetyl-l-cysteine capped quantum dots offer neuronal cell protection by inhibiting beta (1-40) amyloid fibrillation.
Biomater Sci
; 1(6): 577-580, 2013 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32481833
17.
Folate-conjugated Fe3O4@SiO2@gold nanorods@mesoporous SiO2 hybrid nanomaterial: a theranostic agent for magnetic resonance imaging and photothermal therapy.
J Mater Chem B
; 1(23): 2934-2942, 2013 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32260860
18.
NSD2 is recruited through its PHD domain to oncogenic gene loci to drive multiple myeloma.
Cancer Res
; 73(20): 6277-88, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23980095
19.
Effect of surface-functionalized nanoparticles on the elongation phase of beta-amyloid (1-40) fibrillogenesis.
Biomaterials
; 33(18): 4443-50, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22459190
20.
p400 is required for E1A to promote apoptosis.
J Biol Chem
; 280(23): 21915-23, 2005 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-15741165