Detalhe da pesquisa
1.
Selective estrogen receptor modulator (SERM) lasofoxifene forms reactive quinones similar to estradiol.
Chem Res Toxicol
; 25(7): 1472-83, 2012 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22642258
2.
Organic Chemical Contaminants in Water System Infrastructure Following Wildfire.
ACS ES T Water
; 2(2): 357-366, 2022 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35647583
3.
Click synthesis of estradiol-cyclodextrin conjugates as cell compartment selective estrogens.
Bioorg Med Chem
; 18(2): 809-21, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20031420
4.
Anti-inflammatory, antiproliferative, and cytoprotective activity of NO chimera nitrates of use in cancer chemoprevention.
Mol Pharmacol
; 74(5): 1381-91, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18676677
5.
Problematic detoxification of estrogen quinones by NAD(P)H-dependent quinone oxidoreductase and glutathione-S-transferase.
Chem Res Toxicol
; 21(7): 1324-9, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18588320
6.
Nitrates and NO-NSAIDs in cancer chemoprevention and therapy: in vitro evidence querying the NO donor functionality.
Nitric Oxide
; 19(2): 115-24, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18485921
7.
Benzothiophene selective estrogen receptor modulators with modulated oxidative activity and receptor affinity.
J Med Chem
; 50(11): 2682-92, 2007 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-17489582
8.
Formation of compound I by photo-oxidation of compound II.
Org Lett
; 7(6): 1193-5, 2005 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-15760172
9.
SERMs attenuate estrogen-induced malignant transformation of human mammary epithelial cells by upregulating detoxification of oxidative metabolites.
Cancer Prev Res (Phila)
; 7(5): 505-15, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24598415
10.
The naphthol selective estrogen receptor modulator (SERM), LY2066948, is oxidized to an o-quinone analogous to the naphthol equine estrogen, equilenin.
Chem Biol Interact
; 196(1-2): 1-10, 2012 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22290292
11.
NO-SSRIs: Nitric Oxide Chimera Drugs Incorporating a Selective Serotonin Reuptake Inhibitor.
ACS Med Chem Lett
; 2(9): 656-661, 2011 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21927645
12.
Proteomic and mass spectroscopic quantitation of protein S-nitrosation differentiates NO-donors.
ACS Chem Biol
; 5(7): 667-80, 2010 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20524644
13.
Quinone formation as a chemoprevention strategy for hybrid drugs: balancing cytotoxicity and cytoprotection.
Chem Res Toxicol
; 20(12): 1903-12, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17975886
14.
Desaturase reactions complicate the use of norcarane as a mechanistic probe. Unraveling the mixture of twenty-plus products formed in enzyme-catalyzed oxidations of norcarane.
J Org Chem
; 72(4): 1121-7, 2007 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-17288366
15.
Products from enzyme-catalyzed oxidations of norcarenes.
J Org Chem
; 72(4): 1128-33, 2007 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-17288367
16.
Cytochrome p450 compound I.
J Am Chem Soc
; 128(14): 4580-1, 2006 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-16594688
17.
Highly reactive electrophilic oxidants in cytochrome P450 catalysis.
Biochem Biophys Res Commun
; 338(1): 394-403, 2005 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-16168951
18.
Hydroxylation by the hydroperoxy-iron species in cytochrome P450 enzymes.
J Am Chem Soc
; 126(1): 115-26, 2004 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-14709076
19.
Kinetic isotope effects implicate two electrophilic oxidants in cytochrome p450-catalyzed hydroxylations.
J Am Chem Soc
; 125(20): 6064-5, 2003 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-12785830