Changes in plasma hydrogen sulfide and nitric oxide levels and their clinical significance in children with Kawasaki disease / 中华医学杂志(英文版)

<p><b>BACKGROUND</b>Cardiac involvement is the most common complication of Kawasaki disease (KD); however, the underlying mechanisms are not understood. The present study was designed to investigate changes in plasma hydrogen sulfide (H(2)S) and nitric oxide (NO) levels in the acute and recovery stages of KD children and to examine their clinical significance.</p><p><b>METHODS</b>Thirty-five KD patients and 32 healthy children were enrolled in the study. KD patients were divided into two subgroups: a non-cardiac involvement group and a cardiac involvement group. Plasma H(2)S levels were measured using the sulfur-sensitive electrode method and plasma NO levels and NO synthase activity were determined using the nitrate reductase method both before and after intravenous immune globulin (IVIG) therapy.</p><p><b>RESULTS</b>Plasma H(2)S levels significantly decreased in KD patients during the acute phase of the disease and NO levels were significantly increased, compared with the control group (P < 0.01). After treatment with IVIG, both plasma H(2)S and NO levels significantly increased (P < 0.01). The plasma levels of H(2)S were significantly lower in the cardiac involvement group compared with the non-cardiac involvement group (P < 0.05).</p><p><b>CONCLUSION</b>H(2)S and NO may play a role in the pathophysiological process of inflammation during the acute phase of KD. Endogenous H(2)S may exert protective effects with respect to cardiac complications in KD.</p>

Statistical analysis of articles, citations and authors in Chinese Journal of Burns from 2003 to 2005 / 中华烧伤杂志

<p><b>OBJECTIVE</b>To study the characteristics of articles, citations and authors in Chinese Journal of Burns (Chin J Burns).</p><p><b>METHODS</b>The date concerning articles, citations and authors of Chin J Burns from 2003 to 2005 were collected and analyzed in terms of bibliographic parameters.</p><p><b>RESULTS</b>There were 741 papers published in Chin J Burns during these 3 years, and papers with funded projects accounted for 19.7%. The average number of articles per issue was 41,with paper density of 0.59, and publication date were 15 months in average after submission. Among these papers, 87.9% of which were shared with co-authors, with a corporation rate of 3.94. The papers with citation accounted for 78.7%, and 90.6% of all the citations came from journals, especially English journals. The Price's indicator was 65.6%.</p><p><b>CONCLUSION</b>Chinese Journal of Burns, an academic journal of high quality, with strong influence, pushes the discipline of Burns medicine in China forward.</p>

Statistical analysis of articles,citations and authors in Chinese Critical Care Medicine from 2005 to 2006 / 中国中西医结合急救杂志

Objective To study the characteristics of articles,citations and authors in Chinese Critical Care Medicine (Chin Crit Care Med).Methods The date about articles,citations and authors of Chin Crit Care Med from 2005 to 2006 were collected and analyzed in terms of bibliomertic parameters.Results There were 612 papers published in Chin Crit Care Med during 2 years and the papers with funded projects were accounted for 63.1%.The authors came from 30 provinces,autonomous regions and municipalities directly under the central government in China.The average number of articles per issue was 26;the paper density was 0.40 and the average period from the date of submission to publication was 5.2 months.Among these papers,87.6% were shared with co-authors,with cooperation rate of 4.40.The papers with citation were accounted for 85.1% and 95.9% of the citations in English came from journals.The Price's index was 58.2%.Conclusion The articles published in Chin Crit Care Med have high quality.It is one of the most important resources of information for researches in this field,and it is also a primary kernel journal in Chinese medicine field.

Location and relative quantity of coumarins in the stem of Dendrobium thyrsiflorum / 药学学报

<p><b>AIM</b>To determine the location and relative quantity of coumarins in the stem of Dendrobium thyrsiflorum Rchb. f. , and to provide a scientific basis for evaluating and utilizing the famous medicinal plant.</p><p><b>METHODS</b>The stems of one, two and three years old, separately, were collected in February. Location and relative quantity of coumarins in the top, middle and basal parts of each stem sample were determined by using laser scanning confocal microscopy (LSCM). ANOVA and Tukey's test were employed in the statistical analysis.</p><p><b>RESULTS</b>The coumarins located mainly in vascular bundles, especially on the walls of the outer fiber cells. There was significant difference or great significant difference exist in every part of the stem from different ages. The values of significant difference were as follows: basal part P = 0.004 (< 0.01); middle part P = 0.009 (< 0.01); top part P = 0.036( < 0.05).</p><p><b>CONCLUSION</b>Two years old stem could be the best choice when collecting Dendrobium thyrsiflorum in Feburary.</p>