Detalhe da pesquisa
1.
Integrated Exposure-Response of Dupilumab in Children, Adolescents, and Adults With Atopic Dermatitis Using Categorical and Continuous Efficacy Assessments: A Population Analysis.
Pharm Res
; 40(11): 2653-2666, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-38082089
2.
Population pharmacokinetic and pharmacokinetic-pharmacodynamic modeling of bempedoic acid and low-density lipoprotein cholesterol in healthy subjects and patients with dyslipidemia.
J Pharmacokinet Pharmacodyn
; 50(5): 351-364, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37243877
3.
Cabozantinib exposure-response analyses of efficacy and safety in patients with advanced hepatocellular carcinoma.
J Pharmacokinet Pharmacodyn
; 46(6): 577-589, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31637577
4.
Population Pharmacokinetics Analysis To Inform Efavirenz Dosing Recommendations in Pediatric HIV Patients Aged 3 Months to 3 Years.
Antimicrob Agents Chemother
; 60(6): 3676-86, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27067333
5.
Population pharmacokinetics of naloxegol in a population of 1247 healthy subjects and patients.
Br J Clin Pharmacol
; 81(1): 89-100, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26317320
6.
A Time-to-Event Exposure-Response Model for Amyloid-Related Imaging Abnormalities Following Administration of Aducanumab to Subjects With Early Alzheimer Disease.
J Clin Pharmacol
; 62(8): 1030-1046, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35285968
7.
Development of a Population Pharmacokinetic Model for the Diroximel Fumarate Metabolites Monomethyl Fumarate and 2-Hydroxyethyl Succinimide Following Oral Administration of Diroximel Fumarate in Healthy Participants and Patients with Multiple Sclerosis.
Neurol Ther
; 11(1): 353-371, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35041178
8.
Pharmacodynamic effect of bempedoic acid and statin combinations: predictions from a dose-response model.
Eur Heart J Cardiovasc Pharmacother
; 8(6): 578-586, 2022 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34448822
9.
Concentration-QTc Modeling of Ozanimod's Major Active Metabolites in Adult Healthy Subjects.
CPT Pharmacometrics Syst Pharmacol
; 10(2): 119-126, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33314790
10.
Population Pharmacokinetics of Vixotrigine in Healthy Volunteers and Subjects with Trigeminal Neuralgia, Painful Lumbosacral Radiculopathy and Erythromelalgia.
Eur J Drug Metab Pharmacokinet
; 46(3): 395-404, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33782834
11.
Population pharmacokinetic analysis of apomorphine sublingual film or subcutaneous apomorphine in healthy subjects and patients with Parkinson's disease.
Clin Transl Sci
; 14(4): 1464-1475, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33650272
12.
Updated Population Pharmacokinetic Model of Cabozantinib Integrating Various Cancer Types Including Hepatocellular Carcinoma.
J Clin Pharmacol
; 59(11): 1551-1561, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31187515
13.
Population Pharmacokinetics of Pregabalin Extended-Release in Healthy Volunteers and Patients With Postherpetic Neuralgia, Fibromyalgia, and Partial-Onset Seizures.
J Clin Pharmacol
; 59(11): 1527-1542, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31183879
14.
Performance characteristics for some typical QT study designs under the ICH E-14 guidance.
J Clin Pharmacol
; 48(2): 215-24, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18199896
15.
Clinical Pharmacokinetics and Pharmacodynamics of Dalcetrapib.
Clin Pharmacokinet
; 57(11): 1359-1367, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29730761
16.
Lurasidone Dose Response in Bipolar Depression: A Population Dose-response Analysis.
Clin Ther
; 38(1): 4-15, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26730454
17.
Pharmacodynamic analysis of the microbiological efficacy of telithromycin in patients with community-acquired pneumonia.
Clin Pharmacokinet
; 44(3): 317-29, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15762772
18.
Pharmacokinetics and safety of the ketolide telithromycin in patients with renal impairment.
J Clin Pharmacol
; 44(3): 234-44, 2004 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-14973302
19.
A comparison of the pharmacokinetics and pharmacodynamics of pregabalin and gabapentin.
Clin Pharmacokinet
; 49(10): 661-9, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20818832
20.
Exposure-response analysis in patients with schizophrenia to assess the effect of asenapine on QTc prolongation.
J Clin Pharmacol
; 49(11): 1297-308, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19843656