Detalhe da pesquisa
1.
Pegbelfermin in Patients With Nonalcoholic Steatohepatitis and Stage 3 Fibrosis (FALCON 1): A Randomized Phase 2b Study.
Clin Gastroenterol Hepatol
; 22(1): 102-112.e9, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37088457
2.
Pegbelfermin in Patients With Nonalcoholic Steatohepatitis and Compensated Cirrhosis (FALCON 2): A Randomized Phase 2b Study.
Clin Gastroenterol Hepatol
; 22(1): 113-123.e9, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37088458
3.
BMS-986263 in patients with advanced hepatic fibrosis: 36-week results from a randomized, placebo-controlled phase 2 trial.
Hepatology
; 75(4): 912-923, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34605045
4.
Evaluation of a PEGylated Fibroblast Growth Factor 21 Variant Using Novel Preclinical Magnetic Resonance Imaging and Magnetic Resonance Elastography in a Mouse Model of Nonalcoholic Steatohepatitis.
J Magn Reson Imaging
; 56(3): 712-724, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35092323
5.
Combined Therapy with a CCR2/CCR5 Antagonist and FGF21 Analogue Synergizes in Ameliorating Steatohepatitis and Fibrosis.
Int J Mol Sci
; 23(12)2022 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35743140
6.
Pegbelfermin (BMS-986036), a PEGylated fibroblast growth factor 21 analogue, in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 2a trial.
Lancet
; 392(10165): 2705-2717, 2019 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30554783
7.
Somatic hypermutations confer rheumatoid factor activity in hepatitis C virus-associated mixed cryoglobulinemia.
Arthritis Rheum
; 65(9): 2430-40, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23754128
8.
Clonal B cells in patients with hepatitis C virus-associated mixed cryoglobulinemia contain an expanded anergic CD21low B-cell subset.
Blood
; 117(20): 5425-37, 2011 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21421840
9.
Pharmacokinetics, safety, and tolerability of BMS-986263, a lipid nanoparticle containing HSP47 siRNA, in participants with hepatic impairment.
Clin Transl Sci
; 16(10): 1791-1802, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37654022
10.
Effect of pegbelfermin on NASH and fibrosis-related biomarkers and correlation with histological response in the FALCON 1 trial.
JHEP Rep
; 5(4): 100661, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36866389
11.
Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures.
Hepatology
; 54(6): 1913-23, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21800339
12.
Pegbelfermin selectively reduces secondary bile acid concentrations in patients with non-alcoholic steatohepatitis.
JHEP Rep
; 4(1): 100392, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34977519
13.
MGAT2 inhibitor decreases liver fibrosis and inflammation in murine NASH models and reduces body weight in human adults with obesity.
Cell Metab
; 34(11): 1732-1748.e5, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36323235
14.
SOMAscan Proteomics Identifies Serum Biomarkers Associated With Liver Fibrosis in Patients With NASH.
Hepatol Commun
; 5(5): 760-773, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-34027267
15.
Phase 2 trial design of BMS-986278, a lysophosphatidic acid receptor 1 (LPA1) antagonist, in patients with idiopathic pulmonary fibrosis (IPF) or progressive fibrotic interstitial lung disease (PF-ILD).
BMJ Open Respir Res
; 8(1)2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34969771
16.
The FALCON program: Two phase 2b randomized, double-blind, placebo-controlled studies to assess the efficacy and safety of pegbelfermin in the treatment of patients with nonalcoholic steatohepatitis and bridging fibrosis or compensated cirrhosis.
Contemp Clin Trials
; 104: 106335, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33657443
17.
Hepatitis C virus-induced cryoglobulinemia.
Kidney Int
; 76(8): 818-24, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19606079
18.
Cell culture-produced hepatitis C virus does not infect peripheral blood mononuclear cells.
Hepatology
; 48(6): 1843-50, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19003912
19.
Pegbelfermin (BMS-986036), PEGylated FGF21, in Patients with Obesity and Type 2 Diabetes: Results from a Randomized Phase 2 Study.
Obesity (Silver Spring)
; 27(1): 41-49, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30520566
20.
Elbasvir/Grazoprevir in People With Hepatitis C Genotype 1 Infection and Child-Pugh Class B Cirrhosis: The C-SALT Study.
Clin Transl Gastroenterol
; 10(4): e00007, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30939489