Detalhe da pesquisa
1.
Isoform-Specific Biased Agonism of Histamine H3 Receptor Agonists.
Mol Pharmacol
; 91(2): 87-99, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27864425
2.
High throughput, quantitative analysis of human osteoclast differentiation and activity.
Anal Biochem
; 519: 51-56, 2017 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27988276
3.
Strategies to address low drug solubility in discovery and development.
Pharmacol Rev
; 65(1): 315-499, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23383426
4.
Label-Free Kinetics: Exploiting Functional Hemi-Equilibrium to Derive Rate Constants for Muscarinic Receptor Antagonists.
Mol Pharmacol
; 88(4): 779-90, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26243731
5.
Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target.
Proc Natl Acad Sci U S A
; 109(42): 16823-8, 2012 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23035243
6.
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria.
Proc Natl Acad Sci U S A
; 108(11): 4400-5, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21300861
7.
Intestinal bile secretion promotes drug absorption from lipid colloidal phases via induction of supersaturation.
Mol Pharm
; 10(5): 1874-89, 2013 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23480483
8.
Computational prediction of drug solubility in lipid based formulation excipients.
Pharm Res
; 30(12): 3225-37, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23771564
9.
A mouse model to evaluate the impact of species, sex, and lipid load on lymphatic drug transport.
Pharm Res
; 30(12): 3254-70, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23430484
10.
Acute hypertriglyceridemia promotes intestinal lymphatic lipid and drug transport: a positive feedback mechanism in lipid and drug absorption.
Mol Pharm
; 8(4): 1132-9, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21604764
11.
A Tribute to Professor Per Artursson - Scientist, Explorer, Mentor, Innovator, and Giant in Pharmaceutical Research.
J Pharm Sci
; 110(1): 2-11, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33096136
12.
Pharmacological Insights Into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure.
Front Pharmacol
; 12: 628060, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33776771
13.
Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers.
Sci Transl Med
; 13(612): eabd5524, 2021 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34550729
14.
Deletion of GPR21 improves glucose homeostasis and inhibits the CCL2-CCR2 axis by divergent mechanisms.
BMJ Open Diabetes Res Care
; 9(2)2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34782333
15.
Targeted drug delivery to lymphocytes: a route to site-specific immunomodulation?
Mol Pharm
; 7(6): 2297-309, 2010 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-20958081
16.
The mechanism of lymphatic access of two cholesteryl ester transfer protein inhibitors (CP524,515 and CP532,623) and evaluation of their impact on lymph lipoprotein profiles.
Pharm Res
; 27(9): 1949-64, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20635194
17.
The role of the intestinal lymphatics in the absorption of two highly lipophilic cholesterol ester transfer protein inhibitors (CP524,515 and CP532,623).
Pharm Res
; 27(5): 878-93, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20221896
18.
The comparative antimalarial properties of weak base and neutral synthetic ozonides.
Bioorg Med Chem Lett
; 20(2): 563-6, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19962893
19.
Identification of an antimalarial synthetic trioxolane drug development candidate.
Nature
; 430(7002): 900-4, 2004 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-15318224
20.
Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs.
Nat Rev Drug Discov
; 6(3): 231-48, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17330072