Detalhe da pesquisa
1.
Gene activation of SMN by selective disruption of lncRNA-mediated recruitment of PRC2 for the treatment of spinal muscular atrophy.
Proc Natl Acad Sci U S A
; 114(8): E1509-E1518, 2017 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28193854
2.
Polysome shift assay for direct measurement of miRNA inhibition by anti-miRNA drugs.
Nucleic Acids Res
; 44(2): e13, 2016 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26384419
3.
The microRNA-130/301 family controls vasoconstriction in pulmonary hypertension.
J Biol Chem
; 290(4): 2069-85, 2015 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25505270
4.
Non-inhibited miRNAs shape the cellular response to anti-miR.
Nucleic Acids Res
; 42(11): 6945-55, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24810853
5.
Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice.
Hum Mol Genet
; 22(20): 4127-35, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23740943
6.
Functional genomics identifies therapeutic targets for MYC-driven cancer.
Proc Natl Acad Sci U S A
; 109(24): 9545-50, 2012 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22623531
7.
Disease-linked microRNA-21 exhibits drastically reduced mRNA binding and silencing activity in healthy mouse liver.
RNA
; 18(8): 1510-26, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22740638
8.
Allele-specific control of rodent and human lncRNA KMT2E-AS1 promotes hypoxic endothelial pathology in pulmonary hypertension.
Sci Transl Med
; 16(729): eadd2029, 2024 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38198571
9.
Coordinated regulation of life and death by RB.
Nat Rev Cancer
; 3(2): 130-8, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12563312
10.
Novel AAV-mediated genome editing therapy improves health and survival in a mouse model of methylmalonic acidemia.
PLoS One
; 17(9): e0274774, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36126056
11.
Aven-dependent activation of ATM following DNA damage.
Curr Biol
; 18(13): 933-42, 2008 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-18571408
12.
Signal-dependent protection from apoptosis in mice expressing caspase-resistant Rb.
Nat Cell Biol
; 4(10): 757-65, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12360286
13.
What goes up must come down: the emerging role of microRNA in fibrosis.
Hepatology
; 53(1): 4-6, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21254156
14.
Tumor necrosis factor alpha-induced apoptosis requires p73 and c-ABL activation downstream of RB degradation.
Mol Cell Biol
; 24(10): 4438-47, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15121862
15.
Lipid Nanoparticle-Mediated Delivery of Anti-miR-17 Family Oligonucleotide Suppresses Hepatocellular Carcinoma Growth.
Mol Cancer Ther
; 16(5): 905-913, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28167506
16.
Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension.
J Clin Invest
; 132(10)2022 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35575096
17.
Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit.
Cell Rep
; 13(5): 1016-32, 2015 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26565914
18.
Anti-microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways.
J Clin Invest
; 125(1): 141-56, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25415439
19.
Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension.
EMBO Mol Med
; 7(6): 695-713, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25825391
20.
Anti-miRs competitively inhibit microRNAs in Argonaute complexes.
PLoS One
; 9(7): e100951, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24992387