Detalhe da pesquisa
1.
Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration.
Cell
; 186(6): 1162-1178.e20, 2023 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36931244
2.
Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis.
Cell
; 183(6): 1617-1633.e22, 2020 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33259802
3.
SMARCA4 vulnerability in H3K27M midline glioma: A silver bullet for a lethal disease.
Mol Cell
; 83(2): 163-164, 2023 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36669477
4.
Histone H3.3 K27M and K36M mutations de-repress transposable elements through perturbation of antagonistic chromatin marks.
Mol Cell
; 81(23): 4876-4890.e7, 2021 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34739871
5.
H3S10ph broadly marks early-replicating domains in interphase ESCs and shows reciprocal antagonism with H3K9me2.
Genome Res
; 28(1): 37-51, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29229671
6.
Oncohistones in brain tumors: the soil and seed.
Trends Cancer
; 9(5): 444-455, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36933956
7.
H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone.
Cancer Discov
; 10(12): 1968-1987, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32967858
8.
H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis.
Nat Commun
; 10(1): 1262, 2019 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30890717
9.
Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas.
Cancer Cell
; 35(5): 782-797.e8, 2019 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31085178
10.
Mutant H3 histones drive human pre-leukemic hematopoietic stem cell expansion and promote leukemic aggressiveness.
Nat Commun
; 10(1): 2891, 2019 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31253791
11.
Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas.
Cancer Cell
; 36(3): 338-339, 2019 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31526762