Detalhe da pesquisa
1.
Hypoxia Inducible Factor-1α binds and activates γ-secretase for Aß production under hypoxia and cerebral hypoperfusion.
Mol Psychiatry
; 27(10): 4264-4273, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35764706
2.
Targeting Solid Tumors Using CD3 Bispecific Antibodies.
Mol Cancer Ther
; 20(8): 1350-1358, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34045228
3.
Generation of T-cell-redirecting bispecific antibodies with differentiated profiles of cytokine release and biodistribution by CD3 affinity tuning.
Sci Rep
; 11(1): 14397, 2021 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34257348
4.
A PSMA-Targeting CD3 Bispecific Antibody Induces Antitumor Responses that Are Enhanced by 4-1BB Costimulation.
Cancer Immunol Res
; 8(5): 596-608, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32184296
5.
A class of costimulatory CD28-bispecific antibodies that enhance the antitumor activity of CD3-bispecific antibodies.
Sci Transl Med
; 12(525)2020 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31915305
6.
A Mucin 16 bispecific T cell-engaging antibody for the treatment of ovarian cancer.
Sci Transl Med
; 11(497)2019 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31217340
7.
Complex regulation of γ-secretase: from obligatory to modulatory subunits.
Front Aging Neurosci
; 6: 342, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25610395
8.
Nontranscriptional role of Hif-1α in activation of γ-secretase and notch signaling in breast cancer.
Cell Rep
; 8(4): 1077-92, 2014 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25131208