Detalhe da pesquisa
1.
A Novel Dual-Fc Bispecific Antibody with Enhanced Fc Effector Function.
Biochemistry
; 63(8): 958-968, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38426700
2.
Discovery of amivantamab (JNJ-61186372), a bispecific antibody targeting EGFR and MET.
J Biol Chem
; 296: 100641, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33839159
3.
Design and characterization of novel dual Fc antibody with enhanced avidity for Fc receptors.
Proteins
; 88(5): 689-697, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31702857
4.
Kinetic mechanism of controlled Fab-arm exchange for the formation of bispecific immunoglobulin G1 antibodies.
J Biol Chem
; 293(2): 651-661, 2018 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29150443
5.
Toward a Combinatorial Approach for the Prediction of IgG Half-Life and Clearance.
Drug Metab Dispos
; 46(12): 1900-1907, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30232177
6.
Diffusion of Soluble Aggregates of THIOMABs and Bispecific Antibodies in Serum.
Biochemistry
; 56(17): 2251-2260, 2017 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28394577
7.
Fc Engineering Approaches to Enhance the Agonism and Effector Functions of an Anti-OX40 Antibody.
J Biol Chem
; 291(53): 27134-27146, 2016 12 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27856634
8.
Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.
Nature
; 471(7336): 110-4, 2011 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21368834
9.
Impact of Cell-surface Antigen Expression on Target Engagement and Function of an Epidermal Growth Factor Receptor × c-MET Bispecific Antibody.
J Biol Chem
; 290(41): 24689-704, 2015 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26260789
10.
An efficient process of generating bispecific antibodies via controlled Fab-arm exchange using culture supernatants.
Protein Expr Purif
; 121: 133-40, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26826313
11.
High-throughput assay for measuring monoclonal antibody self-association and aggregation in serum.
Bioconjug Chem
; 26(3): 520-8, 2015 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25714504
12.
Introduction to the Use of Linear and Nonlinear Regression Analysis in Quantitative Biological Assays.
Curr Protoc
; 3(6): e801, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37358238
13.
Large scale controlled Fab exchange GMP process to prepare bispecific antibodies.
Front Bioeng Biotechnol
; 11: 1298890, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38283167
14.
Expression and purification of human TRPV1 in baculovirus-infected insect cells for structural studies.
Protein Expr Purif
; 65(1): 38-50, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19121396
15.
Antibody Structure and Function: The Basis for Engineering Therapeutics.
Antibodies (Basel)
; 8(4)2019 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31816964
16.
Influence of the bispecific antibody IgG subclass on T cell redirection.
MAbs
; 11(6): 1012-1024, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31242061
17.
Characterization of a Novel Bispecific Antibody That Activates T Cells In Vitro and Slows Tumor Growth In Vivo.
Monoclon Antib Immunodiagn Immunother
; 38(6): 242-254, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31825302
18.
Over-expression, solubilization, and purification of G protein-coupled receptors for structural biology.
Comb Chem High Throughput Screen
; 11(6): 439-62, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18673272
19.
FcγRII-binding Centyrins mediate agonism and antibody-dependent cellular phagocytosis when fused to an anti-OX40 antibody.
MAbs
; 10(3): 463-475, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29359992
20.
Human IgG subclass cross-species reactivity to mouse and cynomolgus monkey Fcγ receptors.
Immunol Lett
; 197: 1-8, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29476755