Detalhe da pesquisa
1.
IL12 integrated into the CAR exodomain converts CD8+ T cells to poly-functional NK-like cells with superior killing of antigen-loss tumors.
Mol Ther
; 30(2): 593-605, 2022 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34678512
2.
Depletion of Collagen IX Alpha1 Impairs Myeloid Cell Function.
Stem Cells
; 36(11): 1752-1763, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30063808
3.
CAR T Cells with Enhanced Sensitivity to B Cell Maturation Antigen for the Targeting of B Cell Non-Hodgkin's Lymphoma and Multiple Myeloma.
Mol Ther
; 26(8): 1906-1920, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30078440
4.
Coexpressed Catalase Protects Chimeric Antigen Receptor-Redirected T Cells as well as Bystander Cells from Oxidative Stress-Induced Loss of Antitumor Activity.
J Immunol
; 196(2): 759-66, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26673145
5.
Of CARs and TRUCKs: chimeric antigen receptor (CAR) T cells engineered with an inducible cytokine to modulate the tumor stroma.
Immunol Rev
; 257(1): 83-90, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24329791
6.
Superior Therapeutic Index in Lymphoma Therapy: CD30(+) CD34(+) Hematopoietic Stem Cells Resist a Chimeric Antigen Receptor T-cell Attack.
Mol Ther
; 24(8): 1423-34, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-27112062
7.
T cells expressing a chimeric antigen receptor that binds hepatitis B virus envelope proteins control virus replication in mice.
Gastroenterology
; 145(2): 456-65, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23639914
8.
An anti-CD19/CTLA-4 switch improves efficacy and selectivity of CAR T cells targeting CD80/86-upregulated DLBCL.
Cell Rep Med
; 5(2): 101421, 2024 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38340727
9.
Redirected T cells that target pancreatic adenocarcinoma antigens eliminate tumors and metastases in mice.
Gastroenterology
; 143(5): 1375-1384.e5, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22819865
10.
T cells that target carcinoembryonic antigen eradicate orthotopic pancreatic carcinomas without inducing autoimmune colitis in mice.
Gastroenterology
; 143(4): 1095-107.e2, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22750462
11.
Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies.
Blood Cancer Discov
; 4(1): 78-97, 2023 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36346827
12.
CAR T cells transform to trucks: chimeric antigen receptor-redirected T cells engineered to deliver inducible IL-12 modulate the tumour stroma to combat cancer.
Cancer Immunol Immunother
; 61(8): 1269-77, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22274776
13.
CD28 costimulation Impairs the efficacy of a redirected t-cell antitumor attack in the presence of regulatory t cells which can be overcome by preventing Lck activation.
Mol Ther
; 19(4): 760-7, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21326215
14.
Regulatory CAR-T cells in autoimmune diseases: Progress and current challenges.
Front Immunol
; 13: 934343, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36032080
15.
Review: Sustainable Clinical Development of CAR-T Cells - Switching From Viral Transduction Towards CRISPR-Cas Gene Editing.
Front Immunol
; 13: 865424, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35784280
16.
Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas.
Proc Natl Acad Sci U S A
; 105(45): 17481-6, 2008 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-18987320
17.
CXCR5 CAR-T cells simultaneously target B cell non-Hodgkin's lymphoma and tumor-supportive follicular T helper cells.
Nat Commun
; 12(1): 240, 2021 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33431832
18.
T cells redirected against hepatitis B virus surface proteins eliminate infected hepatocytes.
Gastroenterology
; 134(1): 239-47, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18166356
19.
FimH-based display of functional eukaryotic proteins on bacteria surfaces.
Sci Rep
; 9(1): 8410, 2019 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31182802
20.
CAR T Cells Releasing IL-18 Convert to T-Bethigh FoxO1low Effectors that Exhibit Augmented Activity against Advanced Solid Tumors.
Cell Rep
; 21(11): 3205-3219, 2017 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29241547