Detalhe da pesquisa
1.
Small Change, Big Impact: Reversal of Diastereoselection in Cuprate Conjugate Additions to α,ß-Unsaturated Lactams and Identification of a Competing Mechanism.
J Org Chem
; 88(7): 4387-4396, 2023 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36940148
2.
Visible Light Photoredox-Catalyzed Decarboxylative Alkylation of 3-Aryl-Oxetanes and Azetidines via Benzylic Tertiary Radicals and Implications of Benzylic Radical Stability.
J Org Chem
; 88(10): 6476-6488, 2023 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36868184
3.
Synthesis of oxetane and azetidine ethers as ester isosteres by Brønsted acid catalysed alkylation of alcohols with 3-aryl-oxetanols and 3-aryl-azetidinols.
Org Biomol Chem
; 21(27): 5553-5559, 2023 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37345459
4.
Synthesis of 3-Aryl-3-Sulfanyl Azetidines by Iron-Catalyzed Thiol Alkylation with N-Cbz Azetidinols.
J Org Chem
; 84(9): 5943-5956, 2019 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30973723
5.
Lithium-Catalyzed Thiol Alkylation with Tertiary and Secondary Alcohols: Synthesis of 3-Sulfanyl-Oxetanes as Bioisosteres.
Chemistry
; 24(4): 818-821, 2018 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29181870
6.
Visible-Light-Initiated Manganese Catalysis for C-H Alkylation of Heteroarenes: Applications and Mechanistic Studies.
Angew Chem Int Ed Engl
; 56(48): 15309-15313, 2017 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28960645
7.
Structurally Divergent Lithium Catalyzed Friedel-Crafts Reactions on Oxetan-3-ols: Synthesis of 3,3-Diaryloxetanes and 2,3-Dihydrobenzofurans.
Chemistry
; 22(45): 16271-16276, 2016 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27723135
8.
Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors.
Biochem J
; 460(2): 211-22, 2014 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24593284
9.
The prosthetic rehabilitation of a panfacial fracture patient after reduction: a clinical report.
J Prosthet Dent
; 108(2): 123-8, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22867809
10.
Oxetan-3-ols as 1,2-bis-Electrophiles in a Brønsted-Acid-Catalyzed Synthesis of 1,4-Dioxanes.
Org Lett
; 24(12): 2365-2370, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35311271
11.
Amino-oxetanes as amide isosteres by an alternative defluorosulfonylative coupling of sulfonyl fluorides.
Nat Chem
; 14(2): 160-169, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35087220
12.
Synthesis of Deuterated Heterocycles with Me2NCD(OMe)2 and Evaluation of the Products for Metabolism by Aldehyde Oxidase.
ACS Med Chem Lett
; 13(2): 250-256, 2022 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35178182
13.
Discovery of a Series of Pyrimidine Carboxamides as Inhibitors of Vanin-1.
J Med Chem
; 65(1): 757-784, 2022 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34967602
14.
Design and evaluation of a 2-(2,3,6-trifluorophenyl)acetamide derivative as an agonist of the GPR119 receptor.
Bioorg Med Chem Lett
; 21(5): 1306-9, 2011 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21310611
15.
Investigating 3,3-diaryloxetanes as potential bioisosteres through matched molecular pair analysis.
RSC Med Chem
; 12(12): 2045-2052, 2021 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35024613
16.
PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease.
J Med Chem
; 64(1): 326-342, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33356244
17.
Short Synthesis of Oxetane and Azetidine 3-Aryl-3-carboxylic Acid Derivatives by Selective Furan Oxidative Cleavage.
Org Lett
; 22(14): 5279-5283, 2020 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32338914
18.
Influence of the wastewater composition on denitrification and biological P-removal in the S-DN-P process: (c) dissolved and undissolved substrates.
J Environ Sci (China)
; 21(8): 1074-9, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19862920
19.
Synthesis of 3,3-Diarylazetidines by Calcium(II)-Catalyzed Friedel-Crafts Reaction of Azetidinols with Unexpected Cbz Enhanced Reactivity.
Org Lett
; 21(1): 300-304, 2019 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30582708
20.
Substituted pyrazoles as hepatoselective HMG-CoA reductase inhibitors: discovery of (3R,5R)-7-[2-(4-fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of hypercholesterolemia.
J Med Chem
; 51(1): 31-45, 2008 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-18072721