Detalhe da pesquisa
1.
NURR1 expression regulates retinal pigment epithelial-mesenchymal transition and age-related macular degeneration phenotypes.
Proc Natl Acad Sci U S A
; 119(28): e2202256119, 2022 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35867766
2.
CD68: Potential Contributor to Inflammation and RPE Cell Dystrophy.
Adv Exp Med Biol
; 1415: 207-213, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37440035
3.
Characterization and identification of measurable endpoints in a mouse model featuring age-related retinal pathologies: a platform to test therapies.
Lab Invest
; 102(10): 1132-1142, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35589984
4.
Osteopontin accumulates in basal deposits of human eyes with age-related macular degeneration and may serve as a biomarker of aging.
Mod Pathol
; 35(2): 165-176, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34389792
5.
The Aryl Hydrocarbon Receptor: A Mediator and Potential Therapeutic Target for Ocular and Non-Ocular Neurodegenerative Diseases.
Int J Mol Sci
; 21(18)2020 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32947781
6.
A Review of Pathogenic Drivers of Age-Related Macular Degeneration, Beyond Complement, with a Focus on Potential Endpoints for Testing Therapeutic Interventions in Preclinical Studies.
Adv Exp Med Biol
; 1185: 9-13, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31884581
7.
Suppression of aberrant choroidal neovascularization through activation of the aryl hydrocarbon receptor.
Biochim Biophys Acta Mol Basis Dis
; 1864(5 Pt A): 1583-1595, 2018 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-29481912
8.
Aryl hydrocarbon receptor knock-out exacerbates choroidal neovascularization via multiple pathogenic pathways.
J Pathol
; 235(1): 101-12, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25186463
9.
A Brief Discussion on Lipid Activated Nuclear Receptors and their Potential Role in Regulating Microglia in Age-Related Macular Degeneration (AMD).
Adv Exp Med Biol
; 854: 45-51, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26427392
10.
Tumor-induced loss of mural Connexin 43 gap junction activity promotes endothelial proliferation.
BMC Cancer
; 15: 427, 2015 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26002762
11.
Mutually exclusive inactivation of DMP1 and ARF/p53 in lung cancer.
Cancer Cell
; 12(4): 381-94, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17936562
12.
Potential therapeutic targets for age-related macular degeneration: The nuclear option.
Prog Retin Eye Res
; 94: 101130, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36220751
13.
Internalization of Angiotensin-(1-12) in Adult Retinal Pigment Epithelial-19 Cells.
J Ocul Pharmacol Ther
; 39(4): 290-299, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36944130
14.
Gene Delivery of a Caspase Activation and Recruitment Domain Improves Retinal Pigment Epithelial Function and Modulates Inflammation in a Mouse Model with Features of Dry Age-Related Macular Degeneration.
J Ocul Pharmacol Ther
; 38(5): 359-371, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35446130
15.
LXRs regulate features of age-related macular degeneration and may be a potential therapeutic target.
JCI Insight
; 5(1)2020 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31829999
16.
Models of retinal diseases and their applicability in drug discovery.
Expert Opin Drug Discov
; 13(4): 359-377, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29382242
17.
Impaired monocyte cholesterol clearance initiates age-related retinal degeneration and vision loss.
JCI Insight
; 3(17)2018 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30185655
18.
Rethinking Nuclear Receptors as Potential Therapeutic Targets for Retinal Diseases.
J Biomol Screen
; 21(10): 1007-1018, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27455994
19.
PPARß/δ selectively regulates phenotypic features of age-related macular degeneration.
Aging (Albany NY)
; 8(9): 1952-1978, 2016 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27622388