Detalhe da pesquisa
1.
Base-Displaced Intercalated Structure of the 3-(2-Deoxy-ß-D-erythropentofuranosyl)-pyrimido[1,2-f]purine-6,10(3H,5H)-dione (6-oxo-M1dG) Lesion in DNA.
Chem Res Toxicol
; 36(12): 1947-1960, 2023 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37989274
2.
Escherichia coli YcaQ is a DNA glycosylase that unhooks DNA interstrand crosslinks.
Nucleic Acids Res
; 48(13): 7005-7017, 2020 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32409837
3.
A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins
; 89(11): 1399-1412, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34156100
4.
Site-Specific Synthesis of Oligonucleotides Containing 6-Oxo-M1dG, the Genomic Metabolite of M1dG, and Liquid Chromatography-Tandem Mass Spectrometry Analysis of Its In Vitro Bypass by Human Polymerase ι.
Chem Res Toxicol
; 34(12): 2567-2578, 2021 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34860508
5.
Optimization of ether and aniline based inhibitors of lactate dehydrogenase.
Bioorg Med Chem Lett
; 41: 127974, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33771585
6.
Fragment-based screening of programmed death ligand 1 (PD-L1).
Bioorg Med Chem Lett
; 29(6): 786-790, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30728114
7.
Next-generation sequencing reveals the biological significance of the N(2),3-ethenoguanine lesion in vivo.
Nucleic Acids Res
; 43(11): 5489-500, 2015 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25837992
8.
Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase η and Sulfolobus solfataricus P2 Polymerase IV.
J Am Chem Soc
; 137(22): 7011-4, 2015 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25988947
9.
Characterization of nitrogen mustard formamidopyrimidine adduct formation of bis(2-chloroethyl)ethylamine with calf thymus DNA and a human mammary cancer cell line.
Chem Res Toxicol
; 28(9): 1850-60, 2015 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26285869
10.
Synthesis and characterization of oligonucleotides containing a nitrogen mustard formamidopyrimidine monoadduct of deoxyguanosine.
Chem Res Toxicol
; 27(9): 1610-8, 2014 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25136769
11.
An HPLC-tandem mass spectrometry method for simultaneous detection of alkylated base excision repair products.
Methods
; 64(1): 59-66, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23876937
12.
STING-Pathway Inhibiting Nanoparticles (SPINs) as a Platform for Treatment of Inflammatory Diseases.
ACS Appl Bio Mater
; 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38563162
13.
A Cancer Nanovaccine for Co-Delivery of Peptide Neoantigens and Optimized Combinations of STING and TLR4 Agonists.
ACS Nano
; 18(9): 6845-6862, 2024 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38386282
14.
Depurination of N7-methylguanine by DNA glycosylase AlkD is dependent on the DNA backbone.
Biochemistry
; 52(42): 7363-5, 2013 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24090276
15.
Basis of miscoding of the DNA adduct N2,3-ethenoguanine by human Y-family DNA polymerases.
J Biol Chem
; 287(42): 35516-35526, 2012 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22910910
16.
Mutagenic spectra arising from replication bypass of the 2,6-diamino-4-hydroxy-N(5)-methyl formamidopyrimidine adduct in primate cells.
Chem Res Toxicol
; 26(7): 1108-14, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23763662
17.
Ring-opening of the γ-OH-PdG adduct promotes error-free bypass by the Sulfolobus solfataricus DNA polymerase Dpo4.
Chem Res Toxicol
; 26(9): 1348-60, 2013 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-23947567
18.
Simplified synthesis of individual stereoisomers of the 4-hydroxynonenal adducts of deoxyguanosine.
Tetrahedron Lett
; 54(32): 4289-4291, 2013 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23935223
19.
The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo.
Proc Natl Acad Sci U S A
; 107(11): 4925-30, 2010 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20185759
20.
STING-activating nanoparticles normalize the vascular-immune interface to potentiate cancer immunotherapy.
Sci Immunol
; 8(83): eadd1153, 2023 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37146128