Detalhe da pesquisa
1.
A single-cell atlas identifies pretreatment features of primary imatinib resistance in chronic myeloid leukemia.
Blood
; 141(22): 2738-2755, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36857629
2.
Ponatinib dose-ranging study in chronic-phase chronic myeloid leukemia: a randomized, open-label phase 2 clinical trial.
Blood
; 138(21): 2042-2050, 2021 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34407543
3.
An integrative model of pathway convergence in genetically heterogeneous blast crisis chronic myeloid leukemia.
Blood
; 135(26): 2337-2353, 2020 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32157296
4.
Ponatinib after failure of second-generation tyrosine kinase inhibitor in resistant chronic-phase chronic myeloid leukemia.
Am J Hematol
; 97(11): 1419-1426, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36054756
5.
Application of High Throughput Technologies in the Development of Acute Myeloid Leukemia Therapy: Challenges and Progress.
Int J Mol Sci
; 23(5)2022 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35270002
6.
Simvastatin enhances the efficacy of nilotinib in chronic myeloid leukaemia by post-translational modification and drug transporter modulation.
Anticancer Drugs
; 32(5): 526-536, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33587350
7.
Ponatinib efficacy and safety in Philadelphia chromosome-positive leukemia: final 5-year results of the phase 2 PACE trial.
Blood
; 132(4): 393-404, 2018 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29567798
8.
Overall survival with ponatinib versus allogeneic stem cell transplantation in Philadelphia chromosome-positive leukemias with the T315I mutation.
Cancer
; 123(15): 2875-2880, 2017 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28387926
9.
Phase 1 dose escalation multicenter trial of pracinostat alone and in combination with azacitidine in patients with advanced hematologic malignancies.
Cancer
; 123(24): 4851-4859, 2017 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28841236
10.
Ponatinib versus imatinib for newly diagnosed chronic myeloid leukaemia: an international, randomised, open-label, phase 3 trial.
Lancet Oncol
; 17(5): 612-21, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27083332
11.
Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibition.
Blood
; 123(21): 3316-26, 2014 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24705490
12.
Early response with dasatinib or imatinib in chronic myeloid leukemia: 3-year follow-up from a randomized phase 3 trial (DASISION).
Blood
; 123(4): 494-500, 2014 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24311723
13.
Regulation of myeloid leukaemia by the cell-fate determinant Musashi.
Nature
; 466(7307): 765-8, 2010 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-20639863
14.
Targeting of the MNK-eIF4E axis in blast crisis chronic myeloid leukemia inhibits leukemia stem cell function.
Proc Natl Acad Sci U S A
; 110(25): E2298-307, 2013 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23737503
15.
Final analysis of the efficacy and safety of omacetaxine mepesuccinate in patients with chronic- or accelerated-phase chronic myeloid leukemia: Results with 24 months of follow-up.
Cancer
; 121(10): 1637-44, 2015 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25586015
16.
Phase 2 study of subcutaneous omacetaxine mepesuccinate after TKI failure in patients with chronic-phase CML with T315I mutation.
Blood
; 120(13): 2573-80, 2012 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22896000
17.
Results from HARMONY: an open-label, multicenter, 2-arm, phase 1b, dose-finding study assessing the safety and efficacy of the oral combination of ruxolitinib and buparlisib in patients with myelofibrosis.
Haematologica
; 104(12): e551-e554, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31073072
18.
The cardioprotective potential of sodium-glucose cotransporter 2-inhibitors in breast cancer therapy-related cardiac dysfunction - A systematic review.
Curr Probl Cardiol
; 49(3): 102372, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38281354
19.
Dose modification dynamics of ponatinib in patients with chronic-phase chronic myeloid leukemia (CP-CML) from the PACE and OPTIC trials.
Leukemia
; 38(3): 475-481, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38287132
20.
Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia.
N Engl J Med
; 362(24): 2260-70, 2010 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20525995