Detalhe da pesquisa
1.
Inhaled Medicines: Past, Present, and Future.
Pharmacol Rev
; 74(1): 48-118, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34987088
2.
Dipeptidyl peptidase-1 inhibition with brensocatib reduces the activity of all major neutrophil serine proteases in patients with bronchiectasis: results from the WILLOW trial.
Respir Res
; 24(1): 133, 2023 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37198686
3.
Assessment of Inhaled Treprostinil Palmitil, Inhaled and Intravenous Treprostinil, and Oral Selexipag in a Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension.
J Pharmacol Exp Ther
; 383(1): 103-116, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36507843
4.
Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections.
Antimicrob Agents Chemother
; 65(7): e0031621, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33941518
5.
Treprostinil palmitil, an inhaled long-acting pulmonary vasodilator, does not show tachyphylaxis with daily dosing in rats.
Pulm Pharmacol Ther
; 66: 101983, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33346142
6.
Prostanoid receptor subtypes involved in treprostinil-mediated vasodilation of rat pulmonary arteries and in treprostinil-mediated inhibition of collagen gene expression of human lung fibroblasts.
Prostaglandins Other Lipid Mediat
; 152: 106486, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33011365
7.
Development and Characterization of Treprostinil Palmitil Inhalation Aerosol for the Investigational Treatment of Pulmonary Arterial Hypertension.
Int J Mol Sci
; 22(2)2021 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33430435
8.
Nanoscale Probing of Liposome Encapsulating Drug Nanocrystal Using Atomic Force Microscopy-Infrared Spectroscopy.
Anal Chem
; 92(14): 9922-9931, 2020 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32551576
9.
Changes in respiratory symptoms during 48-week treatment with ARD-3150 (inhaled liposomal ciprofloxacin) in bronchiectasis: results from the ORBIT-3 and -4 studies.
Eur Respir J
; 56(4)2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32554534
10.
Solid State Characterization of Ciprofloxacin Liposome Nanocrystals.
Mol Pharm
; 16(1): 184-194, 2019 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30495965
11.
Direct Comparison of Standard Transmission Electron Microscopy and Cryogenic-TEM in Imaging Nanocrystals Inside Liposomes.
Mol Pharm
; 16(4): 1775-1781, 2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30810323
12.
Effective Treatment of Mycobacterium avium subsp. hominissuis and Mycobacterium abscessus Species Infections in Macrophages, Biofilm, and Mice by Using Liposomal Ciprofloxacin.
Antimicrob Agents Chemother
; 62(10)2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30012773
13.
Sweetening Inhaled Antibiotic Treatment for Eradication of Chronic Respiratory Biofilm Infection.
Pharm Res
; 35(3): 50, 2018 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29417313
14.
Correction for Plaunt et al., "Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections".
Antimicrob Agents Chemother
; 66(11): e0125622, 2022 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36222535
15.
Tuning Ciprofloxacin Release Profiles from Liposomally Encapsulated Nanocrystalline Drug.
Pharm Res
; 33(11): 2748-62, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27439506
16.
Aerosol performance and long-term stability of surfactant-associated liposomal ciprofloxacin formulations with modified encapsulation and release properties.
AAPS PharmSciTech
; 15(5): 1218-27, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24889736
17.
Inhaled, dual release liposomal ciprofloxacin in non-cystic fibrosis bronchiectasis (ORBIT-2): a randomised, double-blind, placebo-controlled trial.
Thorax
; 68(9): 812-7, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23681906
18.
Effect of Inhalation Profile on Delivery of Treprostinil Palmitil Inhalation Powder.
Pharmaceutics
; 15(3)2023 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36986795
19.
Brensocatib, an oral, reversible inhibitor of dipeptidyl peptidase 1, mitigates interferon-α-accelerated lupus nephritis in mice.
Front Immunol
; 14: 1185727, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37441081
20.
Brensocatib (an oral, reversible inhibitor of dipeptidyl peptidase-1) attenuates disease progression in two animal models of rheumatoid arthritis.
Front Immunol
; 14: 1231047, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37638021