Detalhe da pesquisa
1.
S100A8/A9 drives the formation of procoagulant platelets through GPIbα.
Blood
; 140(24): 2626-2643, 2022 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36026606
2.
Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer.
Blood
; 137(24): 3443-3453, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33512486
3.
Experimental validation of computerised models of clustering of platelet glycoprotein receptors that signal via tandem SH2 domain proteins.
PLoS Comput Biol
; 18(11): e1010708, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36441766
4.
Structure-function relationship of the platelet glycoprotein VI (GPVI) receptor: does it matter if it is a dimer or monomer?
Platelets
; 32(6): 724-732, 2021 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33634725
5.
Trivalent nanobody-based ligands mediate powerful activation of GPVI, CLEC-2, and PEAR1 in human platelets whereas FcγRIIA requires a tetravalent ligand.
J Thromb Haemost
; 22(1): 271-285, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-37813196
6.
Validation of agent-based models of surface receptor oligomerisation.
Trends Pharmacol Sci
; 44(10): 643-646, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37507263
7.
Targeting platelet GPVI with glenzocimab: a novel mechanism for inhibition.
Blood Adv
; 7(7): 1258-1268, 2023 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36375047
8.
Characterizing the binding of glycoprotein VI with nanobody 35 reveals a novel monomeric structure of glycoprotein VI where the conformation of D1+D2 is independent of dimerization.
J Thromb Haemost
; 21(2): 317-328, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36700508
9.
Divalent nanobodies to platelet CLEC-2 can serve as agonists or antagonists.
Commun Biol
; 6(1): 376, 2023 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37029319
10.
Katacine Is a New Ligand of CLEC-2 that Acts as a Platelet Agonist.
Thromb Haemost
; 122(8): 1361-1368, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35170009
11.
Evidence that GPVI is Expressed as a Mixture of Monomers and Dimers, and that the D2 Domain is not Essential for GPVI Activation.
Thromb Haemost
; 121(11): 1435-1447, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33638140
12.
Adenosine and Forskolin Inhibit Platelet Aggregation by Collagen but not the Proximal Signalling Events.
Thromb Haemost
; 119(7): 1124-1137, 2019 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-31129912