Detalhe da pesquisa
1.
Construction of a Shape-Diverse Fragment Set: Design, Synthesis and Screen against Aurora-A Kinase.
Chemistry
; 25(27): 6831-6839, 2019 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31026091
2.
Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-ß-lactamases.
Bioorg Med Chem
; 26(11): 2928-2936, 2018 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29655609
3.
Synthesis and Demonstration of the Biological Relevance of sp3 -rich Scaffolds Distantly Related to Natural Product Frameworks.
Chemistry
; 23(60): 15227-15232, 2017 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28983993
4.
An Unusual Carbohydrate Conformation is Evident in Moraxella catarrhalis Oligosaccharides.
Molecules
; 20(8): 14234-53, 2015 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26251889
5.
Investigation into the feasibility of thioditaloside as a novel scaffold for galectin-3-specific inhibitors.
Chembiochem
; 14(11): 1331-42, 2013 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23864426
6.
Re-amputation and survival following toe amputation: outcome data from a tertiary referral centre.
Ir J Med Sci
; 191(3): 1193-1199, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-34156661
7.
Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia.
J Med Chem
; 65(8): 5975-5989, 2022 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35427125
8.
Urological service provision during the COVID-19 period: the experience from an Irish tertiary centre.
Ir J Med Sci
; 190(2): 455-460, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-32856269
9.
Neoadjuvant chemotherapy for luminal a breast cancer: Factors predictive of histopathologic response and oncologic outcome.
Am J Surg
; 222(2): 368-376, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-33334569
10.
Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source.
J Vis Exp
; (171)2021 05 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34125095
11.
Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19.
Sci Rep
; 11(1): 13208, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34168183
12.
Biochemical analysis of Lgt3, a glycosyltransferase of the bacterium Moraxella catarrhalis.
Biochem Biophys Res Commun
; 393(4): 609-13, 2010 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20153730
13.
Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures.
Commun Chem
; 3(1): 122, 2020 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36703375
14.
Achieving a Good Crystal System for Crystallographic X-Ray Fragment Screening.
Methods Enzymol
; 610: 251-264, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30390801
15.
Aromatic heterocycle galectin-1 interactions for selective single-digit nM affinity ligands.
RSC Adv
; 8(44): 24913-24922, 2018 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35542159
16.
Towards understanding the functional role of the glycosyltransferases involved in the biosynthesis of Moraxella catarrhalis lipooligosaccharide.
FEBS J
; 274(8): 2024-37, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17388814
17.
Gentle, fast and effective crystal soaking by acoustic dispensing.
Acta Crystallogr D Struct Biol
; 73(Pt 3): 246-255, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28291760
18.
Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem Biol
; 12(11): 2906-2914, 2017 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29045126
19.
Identification of a novel glycosyltransferase involved in LOS biosynthesis of Moraxella catarrhalis.
Carbohydr Res
; 341(15): 2600-6, 2006 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-16934238
20.
Publisher Correction: Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19.
Sci Rep
; 11(1): 19633, 2021 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34584208