Detalhe da pesquisa
1.
Efficacy, safety and tolerability of rozanolixizumab in patients with chronic inflammatory demyelinating polyradiculoneuropathy: a randomised, subject-blind, investigator-blind, placebo-controlled, phase 2a trial and open-label extension study.
J Neurol Neurosurg Psychiatry
; 2024 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38729747
2.
Evaluation and Application of a PET Tracer in Preclinical and Phase 1 Studies to Determine the Brain Biodistribution of Minzasolmin (UCB0599).
Mol Imaging Biol
; 26(2): 310-321, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38110790
3.
Understanding the structural and functional differences between mouse thyrotropin-releasing hormone receptors 1 and 2.
Proteins
; 71(2): 783-94, 2008 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17979196
4.
A virtual screen for diverse ligands: discovery of selective G protein-coupled receptor antagonists.
J Am Chem Soc
; 130(15): 5115-23, 2008 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-18357984
5.
Synthesis and biological activity of novel peptide mimetics as melanocortin receptor agonists.
Bioorg Med Chem Lett
; 18(3): 1223-8, 2008 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18078748
6.
Brivaracetam-induced elevation of carbamazepine epoxide levels: A post-hoc analysis from the clinical development program.
Epilepsy Res
; 145: 55-62, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29908435
7.
P2Y1 antagonists: combining receptor-based modeling and QSAR for a quantitative prediction of the biological activity based on consensus scoring.
J Med Chem
; 50(14): 3229-41, 2007 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-17564423
8.
Evaluation of small-molecule modulators of the luteinizing hormone/choriogonadotropin and thyroid stimulating hormone receptors: structure-activity relationships and selective binding patterns.
J Med Chem
; 49(13): 3888-96, 2006 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-16789744
9.
Discovery of orally bioavailable 1,3,4-trisubstituted 2-oxopiperazine-based melanocortin-4 receptor agonists as potential antiobesity agents.
J Med Chem
; 51(19): 6055-66, 2008 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-18771254
10.
MCH-R1 antagonists based on an arginine scaffold: SAR studies on the amino-terminus.
Bioorg Med Chem Lett
; 17(3): 832-5, 2007 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17107794
11.
Novel pyrazolopiperazinone- and pyrrolopiperazinone-based MCH-R1 antagonists.
Bioorg Med Chem Lett
; 17(3): 657-61, 2007 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17174091
12.
Aminomethyl tetrahydronaphthalene ketopiperazine MCH-R1 antagonists--Increasing selectivity over hERG.
Bioorg Med Chem Lett
; 17(3): 819-22, 2007 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17107796
13.
The efficacy and cardiac evaluation of aminomethyl tetrahydronaphthalene ketopiperazines: a novel class of potent MCH-R1 antagonists.
Bioorg Med Chem
; 15(5): 2092-105, 2007 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17236777
14.
A low molecular weight agonist signals by binding to the transmembrane domain of thyroid-stimulating hormone receptor (TSHR) and luteinizing hormone/chorionic gonadotropin receptor (LHCGR).
J Biol Chem
; 281(15): 9841-4, 2006 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-16488885
15.
1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors.
Bioorg Med Chem Lett
; 16(6): 1574-8, 2006 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16386905
16.
Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.
Bioorg Med Chem Lett
; 16(16): 4252-6, 2006 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16759857
17.
Solid-supported synthesis of putative peptide beta-turn mimetics via Ugi reaction for diketopiperazine formation.
J Comb Chem
; 4(6): 584-90, 2002.
Artigo
em Inglês
| MEDLINE | ID: mdl-12425603