Detalhe da pesquisa
1.
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.
Cancer Cell
; 10(5): 375-88, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17097560
2.
The mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor AZD6244 (ARRY-142886) induces growth arrest in melanoma cells and tumor regression when combined with docetaxel.
Clin Cancer Res
; 14(1): 230-9, 2008 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18172275
3.
An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells.
Cancer Res
; 67(1): 209-17, 2007 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17210701
4.
A novel ring-substituted diindolylmethane,1,1-bis[3'-(5-methoxyindolyl)]-1-(p-t-butylphenyl) methane, inhibits extracellular signal-regulated kinase activation and induces apoptosis in acute myelogenous leukemia.
Cancer Res
; 65(7): 2890-8, 2005 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15805291
5.
Development of a conditional in vivo model to evaluate the efficacy of small molecule inhibitors for the treatment of Raf-transformed hematopoietic cells.
Cancer Res
; 65(21): 9962-70, 2005 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16267021
6.
Evidence of gender-and tissue-specific promoter methylation and the potential for ethinylestradiol-induced changes in Japanese medaka (Oryzias latipes) estrogen receptor and aromatase genes.
J Toxicol Environ Health A
; 67(1): 1-22, 2004 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-14668108
7.
Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (obatoclax).
Cancer Res
; 68(9): 3413-20, 2008 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18451169
8.
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Cancer Res
; 68(14): 5743-52, 2008 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18632627
9.
PPARgamma-active triterpenoid CDDO enhances ATRA-induced differentiation in APL.
Cancer Biol Ther
; 6(12): 1967-77, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18075297
10.
A novel mechanism of action of methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate: direct permeabilization of the inner mitochondrial membrane to inhibit electron transport and induce apoptosis.
Mol Pharmacol
; 69(4): 1182-93, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16410408
11.
Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells.
Blood
; 107(4): 1546-54, 2006 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16223781
12.
PML-RARalpha and AML1-ETO translocations are rarely associated with methylation of the RARbeta2 promoter.
Ann Hematol
; 85(10): 689-704, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16832676