Detalhe da pesquisa
1.
Hallmarks of neurodegenerative diseases.
Cell
; 186(4): 693-714, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36803602
2.
A feedforward loop links Gaucher and Parkinson's diseases?
Cell
; 146(1): 9-11, 2011 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21729776
3.
Correction: Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia.
PLoS Biol
; 20(5): e3001621, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35507910
4.
Reelin and stk25 have opposing roles in neuronal polarization and dendritic Golgi deployment.
Cell
; 143(5): 826-36, 2010 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21111240
5.
Lysosomal positioning regulates Rab10 phosphorylation at LRRK2+ lysosomes.
Proc Natl Acad Sci U S A
; 119(43): e2205492119, 2022 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36256825
6.
Genome-Wide Analysis of Structural Variants in Parkinson Disease.
Ann Neurol
; 93(5): 1012-1022, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36695634
7.
Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia.
PLoS Biol
; 19(12): e3001480, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34914695
8.
THAP1 modulates oligodendrocyte maturation by regulating ECM degradation in lysosomes.
Proc Natl Acad Sci U S A
; 118(31)2021 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34312226
9.
Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at 16q11.2 and MAPT H1 loci.
Brain
; 145(12): 4349-4367, 2022 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36074904
10.
DJ-1 is not a deglycase and makes a modest contribution to cellular defense against methylglyoxal damage in neurons.
J Neurochem
; 162(3): 245-261, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35713360
11.
Directing LRRK2 to membranes of the endolysosomal pathway triggers RAB phosphorylation and JIP4 recruitment.
Neurobiol Dis
; 170: 105769, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35580815
12.
Genomewide Association Studies of LRRK2 Modifiers of Parkinson's Disease.
Ann Neurol
; 90(1): 76-88, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33938021
13.
Coding and Noncoding Variation in LRRK2 and Parkinson's Disease Risk.
Mov Disord
; 37(1): 95-105, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34542912
14.
Extracellular clusterin limits the uptake of α-synuclein fibrils by murine and human astrocytes.
Glia
; 69(3): 681-696, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33045109
15.
Correction to: Molecular mechanism of olesoxime-mediated neuroprotection through targeting α-synuclein interaction with mitochondrial VDAC.
Cell Mol Life Sci
; 77(18): 3691-3692, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31919572
16.
Molecular mechanism of olesoxime-mediated neuroprotection through targeting α-synuclein interaction with mitochondrial VDAC.
Cell Mol Life Sci
; 77(18): 3611-3626, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-31760463
17.
Parkinson's disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamics.
J Biol Chem
; 294(15): 5907-5913, 2019 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30796162
18.
Sequential screening nominates the Parkinson's disease associated kinase LRRK2 as a regulator of Clathrin-mediated endocytosis.
Neurobiol Dis
; 141: 104948, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32434048
19.
LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network.
Hum Mol Genet
; 27(2): 385-395, 2018 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29177506
20.
Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice.
Hum Mol Genet
; 27(18): 3257-3271, 2018 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29917075