Detalhe da pesquisa
1.
Targeting SARS-CoV-2 Main Protease: A Successful Story Guided by an In Silico Drug Repurposing Approach.
J Chem Inf Model
; 63(11): 3601-3613, 2023 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37227780
2.
Design, synthesis, biological activity evaluation and structure-activity relationships of new steroidal aromatase inhibitors. The case of C-ring and 7ß substituted steroids.
Bioorg Chem
; 131: 106286, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36459778
3.
Short- and Long-Term Regulation of HuD: A Molecular Switch Mediated by Folic Acid?
Int J Mol Sci
; 24(15)2023 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37569576
4.
Natural Agents as Novel Potential Source of Proteasome Inhibitors with Anti-Tumor Activity: Focus on Multiple Myeloma.
Molecules
; 28(3)2023 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36771100
5.
Exploiting DNA Ligase III addiction of multiple myeloma by flavonoid Rhamnetin.
J Transl Med
; 20(1): 482, 2022 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36273153
6.
ABCC Transporters Mediate the Vacuolar Accumulation of Crocins in Saffron Stigmas.
Plant Cell
; 31(11): 2789-2804, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31548254
7.
From Nature to Synthetic Compounds: Novel 1(N),2,3 Trisubstituted-5-oxopyrrolidines Targeting Multiple Myeloma Cells.
Int J Mol Sci
; 23(21)2022 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36361848
8.
Targeting SARS-CoV-2 nsp13 Helicase and Assessment of Druggability Pockets: Identification of Two Potent Inhibitors by a Multi-Site In Silico Drug Repurposing Approach.
Molecules
; 27(21)2022 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36364347
9.
Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control.
J Antimicrob Chemother
; 76(2): 396-412, 2021 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33254234
10.
Current status of antivirals and druggable targets of SARS CoV-2 and other human pathogenic coronaviruses.
Drug Resist Updat
; 53: 100721, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33132205
11.
Anti-Multiple Myeloma Potential of Secondary Metabolites from Hibiscus sabdariffa-Part 2.
Molecules
; 26(21)2021 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34771006
12.
Natural Products Extracted from Fungal Species as New Potential Anti-Cancer Drugs: A Structure-Based Drug Repurposing Approach Targeting HDAC7.
Molecules
; 25(23)2020 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33255661
13.
Multi-Targeting Bioactive Compounds Extracted from Essential Oils as Kinase Inhibitors.
Molecules
; 25(9)2020 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32384767
14.
Pathway involving the N155H mutation in HIV-1 integrase leads to dolutegravir resistance.
J Antimicrob Chemother
; 73(5): 1158-1166, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29373677
15.
Identification of G-quadruplex DNA/RNA binders: Structure-based virtual screening and biophysical characterization.
Biochim Biophys Acta Gen Subj
; 1861(5 Pt B): 1329-1340, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28025082
16.
Chemoinformatic Database Building and in Silico Hit-Identification of Potential Multi-Targeting Bioactive Compounds Extracted from Mushroom Species.
Molecules
; 22(9)2017 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32961649
17.
Exploring new chemical functionalities to improve aromatase inhibition of steroids.
Bioorg Med Chem
; 24(12): 2823-31, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27160054
18.
Incomplete APOBEC3G/F Neutralization by HIV-1 Vif Mutants Facilitates the Genetic Evolution from CCR5 to CXCR4 Usage.
Antimicrob Agents Chemother
; 59(8): 4870-81, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26055363
19.
SI113, a specific inhibitor of the Sgk1 kinase activity that counteracts cancer cell proliferation.
Cell Physiol Biochem
; 35(5): 2006-18, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25871776
20.
Eriocitrin and Apigenin as New Carbonic Anhydrase VA Inhibitors from a Virtual Screening of Calabrian Natural Products.
Planta Med
; 81(6): 533-40, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25590364