Pesquisa | Biblioteca Virtual em Saúde

1.

The fibrinolysis inhibitor α₂-antiplasmin restricts lymphatic remodelling and metastasis in a mouse model of cancer.

Paquet-Fifield, Sophie; Roufail, Sally; Zhang, You-Fang; Sofian, Trifina; Byrne, David J; Coughlin, Paul B; Fox, Stephen B; Stacker, Steven A; Achen, Marc G.

Growth Factors ; 35(2-3): 61-75, 2017 06.

Artigo em Inglês | MEDLINE | ID: mdl-28697634

2.

Primary analysis of a phase II open-label trial of INCB039110, a selective JAK1 inhibitor, in patients with myelofibrosis.

Mascarenhas, John O; Talpaz, Moshe; Gupta, Vikas; Foltz, Lynda M; Savona, Michael R; Paquette, Ronald; Turner, A Robert; Coughlin, Paul; Winton, Elliott; Burn, Timothy C; O'Neill, Peter; Clark, Jason; Hunter, Deborah; Assad, Albert; Hoffman, Ronald; Verstovsek, Srdan.

Haematologica ; 102(2): 327-335, 2017 02.

Artigo em Inglês | MEDLINE | ID: mdl-27789678

3.

Contribution of conserved lysine residues in the alpha2-antiplasmin C terminus to plasmin binding and inhibition.

Lu, Bernadine G C; Sofian, Trifina; Law, Ruby H P; Coughlin, Paul B; Horvath, Anita J.

J Biol Chem ; 286(28): 24544-52, 2011 Jul 15.

Artigo em Inglês | MEDLINE | ID: mdl-21543325

4.

Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization.

Winkler, Ingrid G; Hendy, Jean; Coughlin, Paul; Horvath, Anita; Lévesque, Jean-Pierre.

J Exp Med ; 201(7): 1077-88, 2005 Apr 04.

Artigo em Inglês | MEDLINE | ID: mdl-15795238

5.

Expression of the serpin centerin defines a germinal center phenotype in B-cell lymphomas.

Paterson, Melinda A; Hosking, Patrick S; Coughlin, Paul B.

Am J Clin Pathol ; 130(1): 117-26, 2008 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-18550480

6.

Molecular characterization of centerin, a germinal centre cell serpin.

Paterson, Melinda A; Horvath, Anita J; Pike, Robert N; Coughlin, Paul B.

Biochem J ; 405(3): 489-94, 2007 Aug 01.

Artigo em Inglês | MEDLINE | ID: mdl-17447896

7.

Antiplasmin: the forgotten serpin?

Coughlin, Paul B.

FEBS J ; 272(19): 4852-7, 2005 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-16176259

8.

Serpins 2005 - fun between the beta-sheets. Meeting report based upon presentations made at the 4th International Symposium on Serpin Structure, Function and Biology (Cairns, Australia).

Whisstock, James C; Bottomley, Stephen P; Bird, Phillip I; Pike, Robert N; Coughlin, Paul.

FEBS J ; 272(19): 4868-73, 2005 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-16176261

9.

Desmoteplase-mediated plasminogen activation and clot lysis are inhibited by the lysine analogue tranexamic acid.

Niego, Be'eri; Horvath, Anita; Coughlin, Paul B; Pugsley, Michael K; Medcalf, Robert L.

Blood Coagul Fibrinolysis ; 19(4): 322-4, 2008 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-18469556

10.

A Community Partnership to Respond to the Heroin and Opioid Abuse Epidemic.

Palombi, Laura C; Vargo, Joe; Bennett, Laura; Hendler, Jared; Coughlin, Paul; Winter, Greta; LaRue, Amy.

J Rural Health ; 33(1): 110-113, 2017 01.

Artigo em Inglês | MEDLINE | ID: mdl-27012943

11.

Two missense mutations identified in venous thrombosis patients impair the inhibitory function of the protein Z dependent protease inhibitor.

Young, Laura K; Birch, Nigel P; Browett, Peter J; Coughlin, Paul B; Horvath, Anita J; Van de Water, Neil S; Ockelford, Paul A; Harper, Paul L.

Thromb Haemost ; 107(5): 854-63, 2012 May.

Artigo em Inglês | MEDLINE | ID: mdl-22399118

12.

The X-ray crystal structure of full-length human plasminogen.

Law, Ruby H P; Caradoc-Davies, Tom; Cowieson, Nathan; Horvath, Anita J; Quek, Adam J; Encarnacao, Joanna Amarante; Steer, David; Cowan, Angus; Zhang, Qingwei; Lu, Bernadine G C; Pike, Robert N; Smith, A Ian; Coughlin, Paul B; Whisstock, James C.

Cell Rep ; 1(3): 185-90, 2012 Mar 29.

Artigo em Inglês | MEDLINE | ID: mdl-22832192

13.

X-ray crystal structure of the fibrinolysis inhibitor alpha2-antiplasmin.

Law, Ruby H P; Sofian, Trifina; Kan, Wan-Ting; Horvath, Anita J; Hitchen, Corinne R; Langendorf, Christopher G; Buckle, Ashley M; Whisstock, James C; Coughlin, Paul B.

Blood ; 111(4): 2049-52, 2008 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-18063751

14.

Stage specific gene expression of serpins and their cognate proteases during myeloid differentiation.

Missen, Melinda A; Haylock, David; Whitty, Genevieve; Medcalf, Robert L; Coughlin, Paul B.

Br J Haematol ; 135(5): 715-24, 2006 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-17107353

15.

The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins.

Horvath, Anita J; Irving, James A; Rossjohn, Jamie; Law, Ruby H; Bottomley, Stephen P; Quinsey, Noelene S; Pike, Robert N; Coughlin, Paul B; Whisstock, James C.

J Biol Chem ; 280(52): 43168-78, 2005 Dec 30.

Artigo em Inglês | MEDLINE | ID: mdl-16141197

16.

The Australian Cancer Anaemia Survey: a snapshot of anaemia in adult patients with cancer.

Seshadri, Tara; Prince, H Miles; Bell, David R; Coughlin, Paul B; James, Philip P B; Richardson, Gary E; Chern, Boris; Briggs, Peter; Norman, John; Olver, Ian N; Karapetis, Chris; Stewart, John.

Med J Aust ; 182(9): 453-7, 2005 May 02.

Artigo em Inglês | MEDLINE | ID: mdl-15865588

17.

A review and comparison of the murine alpha1-antitrypsin and alpha1-antichymotrypsin multigene clusters with the human clade A serpins.

Forsyth, Sharon; Horvath, Anita; Coughlin, Paul.

Genomics ; 81(3): 336-45, 2003 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-12659817

18.

Expression patterns of murine antichymotrypsin-like genes reflect evolutionary divergence at the Serpina3 locus.

Horvath, Anita J; Forsyth, Sharon L; Coughlin, Paul B.

J Mol Evol ; 59(4): 488-97, 2004 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-15638460

19.

Warfarin reversal: consensus guidelines, on behalf of the Australasian Society of Thrombosis and Haemostasis.

Baker, Ross I; Coughlin, Paul B; Gallus, Alex S; Harper, Paul L; Salem, Hatem H; Wood, Erica M.

Med J Aust ; 181(9): 492-7, 2004 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-15516194

20.

Introduction of a mutation in the shutter region of antithrombin (Phe77 --> Leu) increases affinity for heparin and decreases thermal stability.

Quinsey, Noelene S; Fitton, Hazel L; Coughlin, Paul; Whisstock, James C; Dafforn, Timothy R; Carrell, Robin W; Bottomley, Stephen P; Pike, Robert N.

Biochemistry ; 42(34): 10169-73, 2003 Sep 02.

Artigo em Inglês | MEDLINE | ID: mdl-12939144

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