Detalhe da pesquisa
1.
Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer.
Cell
; 184(25): 6119-6137.e26, 2021 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34890551
2.
Enrichment analyses identify shared associations for 25 quantitative traits in over 600,000 individuals from seven diverse ancestries.
Am J Hum Genet
; 109(5): 871-884, 2022 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35349783
3.
Deep self-supervised learning for biosynthetic gene cluster detection and product classification.
PLoS Comput Biol
; 19(5): e1011162, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37220151
4.
Multi-scale inference of genetic trait architecture using biologically annotated neural networks.
PLoS Genet
; 17(8): e1009754, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34411094
5.
Natural variation in the regulation of neurodevelopmental genes modifies flight performance in Drosophila.
PLoS Genet
; 17(3): e1008887, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33735180
6.
A topological data analytic approach for discovering biophysical signatures in protein dynamics.
PLoS Comput Biol
; 18(5): e1010045, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35500014
7.
Estimation of non-null SNP effect size distributions enables the detection of enriched genes underlying complex traits.
PLoS Genet
; 16(6): e1008855, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32542026
8.
Fast and flexible linear mixed models for genome-wide genetics.
PLoS Genet
; 15(2): e1007978, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30735486
9.
Detecting epistasis with the marginal epistasis test in genetic mapping studies of quantitative traits.
PLoS Genet
; 13(7): e1006869, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28746338
10.
Stem cells and extracellular vesicles: biological regulators of physiology and disease.
Am J Physiol Cell Physiol
; 317(2): C155-C166, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30917031
11.
Generative modeling of biological shapes and images using a probabilistic α -shape sampler.
bioRxiv
; 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38260340
12.
Scalable nonparametric clustering with unified marker gene selection for single-cell RNA-seq data.
bioRxiv
; 2024 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38405697
13.
Leveraging the genetic correlation between traits improves the detection of epistasis in genome-wide association studies.
G3 (Bethesda)
; 13(8)2023 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37243672
14.
Uncertainty quantification in variable selection for genetic fine-mapping using bayesian neural networks.
iScience
; 25(7): 104553, 2022 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35769876
15.
MegaLMM: Mega-scale linear mixed models for genomic predictions with thousands of traits.
Genome Biol
; 22(1): 213, 2021 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34301310
16.
The Landscape of Glycogen Synthase Kinase-3 Beta Genomic Alterations in Cancer.
Mol Cancer Ther
; 20(1): 183-190, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33087512
17.
Generating Cell Type-Specific Protein Signatures from Non-symptomatic and Diseased Tissues.
Ann Biomed Eng
; 48(8): 2218-2232, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32303872
18.
Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer.
Nat Genet
; 52(4): 408-417, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32203462
19.
VARIABLE PRIORITIZATION IN NONLINEAR BLACK BOX METHODS: A GENETIC ASSOCIATION CASE STUDY1.
Ann Appl Stat
; 13(2): 958-989, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32542104
20.
Bayesian Approximate Kernel Regression with Variable Selection.
J Am Stat Assoc
; 113(524): 1710-1721, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30799887