Detalhe da pesquisa
1.
Improved biodistribution and enhanced immune response of subunit vaccine using a nanostructure formed by self-assembly of ascorbyl palmitate.
Nanomedicine
; 58: 102749, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38719107
2.
Association between levels of synovial anti-citrullinated peptide antibodies and neutrophil response in patients with rheumatoid arthritis.
Eur J Immunol
; 48(9): 1563-1572, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29879311
3.
Neutrophils exhibit differential requirements for homing molecules in their lymphatic and blood trafficking into draining lymph nodes.
J Immunol
; 193(4): 1966-74, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25015824
4.
TLR7 triggering with polyuridylic acid promotes cross-presentation in CD8α+ conventional dendritic cells by enhancing antigen preservation and MHC class I antigen permanence on the dendritic cell surface.
J Immunol
; 190(3): 948-60, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23284054
5.
A comprehensive analysis of the readability of consent forms for blood transfusion in Spain.
Blood Transfus
; 21(4): 356-363, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36580024
6.
Arginase-dependent suppression by CpG-ODN plus IFA-induced splenic myeloid CD11b(+)Gr1(+) cells.
Immunol Cell Biol
; 90(7): 710-21, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22083526
7.
Identification of novel, water-soluble, 2-amino-N-pyrimidin-4-yl acetamides as A2A receptor antagonists with in vivo efficacy.
J Med Chem
; 51(3): 400-6, 2008 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-18189346
8.
2-Amino-N-pyrimidin-4-ylacetamides as A2A receptor antagonists: 1. Structure-activity relationships and optimization of heterocyclic substituents.
J Med Chem
; 51(6): 1719-29, 2008 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-18307292
9.
2-Amino-N-pyrimidin-4-ylacetamides as A2A receptor antagonists: 2. Reduction of hERG activity, observed species selectivity, and structure-activity relationships.
J Med Chem
; 51(6): 1730-9, 2008 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-18307293
10.
2,6-Diaryl-4-phenacylaminopyrimidines as potent and selective adenosine A(2A) antagonists with reduced hERG liability.
Bioorg Med Chem Lett
; 18(4): 1269-73, 2008 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18249540
11.
2,6-Diaryl-4-acylaminopyrimidines as potent and selective adenosine A(2A) antagonists with improved solubility and metabolic stability.
Bioorg Med Chem Lett
; 18(20): 5402-5, 2008 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18835161
12.
Synthesis of N-pyrimidinyl-2-phenoxyacetamides as adenosine A2A receptor antagonists.
Bioorg Med Chem Lett
; 18(6): 1778-83, 2008 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18329269
13.
Class-B CpG-ODN Formulated With a Nanostructure Induces Type I Interferons-Dependent and CD4+ T Cell-Independent CD8+ T-Cell Response Against Unconjugated Protein Antigen.
Front Immunol
; 9: 2319, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30364187
14.
Aging Impairs the Ability of Conventional Dendritic Cells to Cross-Prime CD8+ T Cells upon Stimulation with a TLR7 Ligand.
PLoS One
; 10(10): e0140672, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26474053
15.
Expansion of myeloid-derived suppressor cells with arginase activity lasts longer in aged than in young mice after CpG-ODN plus IFA treatment.
Oncotarget
; 6(15): 13448-61, 2015 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25922914
16.
Synthesis and biological evaluation of 2-phenylpyran-4-ones: a new class of orally active cyclooxygenase-2 inhibitors.
J Med Chem
; 47(15): 3874-86, 2004 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15239665
17.
Baculovirus capsid display potentiates OVA cytotoxic and innate immune responses.
PLoS One
; 6(8): e24108, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21918683
18.
N-[6-amino-2-(heteroaryl)pyrimidin-4-yl]acetamides as A2A receptor antagonists with improved drug like properties and in vivo efficacy.
J Med Chem
; 52(3): 709-17, 2009 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19140664
19.
Discovery of novel quaternary ammonium derivatives of (3R)-quinuclidinol esters as potent and long-acting muscarinic antagonists with potential for minimal systemic exposure after inhaled administration: identification of (3R)-3-{[hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane bromide (aclidinium bromide).
J Med Chem
; 52(16): 5076-92, 2009 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19653626
20.
Lead optimization of 4-acetylamino-2-(3,5-dimethylpyrazol-1-yl)-6-pyridylpyrimidines as A2A adenosine receptor antagonists for the treatment of Parkinson's disease.
J Med Chem
; 51(22): 7099-110, 2008 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-18947224