Detalhe da pesquisa
1.
Effect of mGluR2 positive allosteric modulation on frontostriatal working memory activation in schizophrenia.
Mol Psychiatry
; 27(2): 1226-1232, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34667261
2.
Schizophrenia risk variants influence multiple classes of transcripts of sorting nexin 19 (SNX19).
Mol Psychiatry
; 25(4): 831-843, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30635639
3.
Comprehensive assessment of multiple biases in small RNA sequencing reveals significant differences in the performance of widely used methods.
BMC Genomics
; 20(1): 513, 2019 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31226924
4.
Differential Pharmacology and Binding of mGlu2 Receptor Allosteric Modulators.
Mol Pharmacol
; 93(5): 526-540, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29545267
5.
Novel inhibitors of As(III) S-adenosylmethionine methyltransferase (AS3MT) identified by virtual screening.
Bioorg Med Chem Lett
; 28(19): 3231-3235, 2018 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30170942
6.
AZD6280, a novel partial γ-aminobutyric acid A receptor modulator, demonstrates a pharmacodynamically selective effect profile in healthy male volunteers.
J Clin Psychopharmacol
; 35(1): 22-33, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25493397
7.
The central nervous system effects of the partial GABA-Aα2,3 -selective receptor modulator AZD7325 in comparison with lorazepam in healthy males.
Br J Clin Pharmacol
; 78(6): 1298-314, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24802722
8.
Derisking Psychiatric Drug Development: The NIMH's Fast Fail Program, A Novel Precompetitive Model.
J Clin Psychopharmacol
; 36(5): 419-21, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27404513
9.
Variation of Human Neural Stem Cells Generating Organizer States In Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates.
Cell Rep
; 31(5): 107599, 2020 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32375049
10.
Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs.
Nat Commun
; 11(1): 462, 2020 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31974374
11.
Metabotropic Glutamate Receptors 2 and 3 as Targets for Treating Nicotine Addiction.
Biol Psychiatry
; 83(11): 947-954, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29301614
12.
Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis.
Nat Neurosci
; 21(8): 1117-1125, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30050107
13.
From bench to bedside: mGluR2 positive allosteric modulators as medications to treat substance use disorders.
Psychopharmacology (Berl)
; 234(9-10): 1347-1355, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27995279
14.
The mGluR2 Positive Allosteric Modulator, AZD8529, and Cue-Induced Relapse to Alcohol Seeking in Rats.
Neuropsychopharmacology
; 41(12): 2932-2940, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27339394
15.
The Novel Metabotropic Glutamate Receptor 2 Positive Allosteric Modulator, AZD8529, Decreases Nicotine Self-Administration and Relapse in Squirrel Monkeys.
Biol Psychiatry
; 78(7): 452-62, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25802079
16.
The effects of the nonselective benzodiazepine lorazepam and the α2 /α3 subunit-selective GABAA receptor modulators AZD7325 and AZD6280 on plasma prolactin levels.
Clin Pharmacol Drug Dev
; 4(2): 149-54, 2015 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27128218
17.
Quantification of the interrelationships of receptor pharmacologies within a tricyclic privileged structural scaffold through application of modified forward selection.
Neuropharmacology
; 77: 475-80, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24490229
18.
Alzheimer's disease research and development: a call for a new research roadmap.
Ann N Y Acad Sci
; 1313: 1-16, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24754377
19.
Characterization of IMPY as a potential imaging agent for beta-amyloid plaques in double transgenic PSAPP mice.
Eur J Nucl Med Mol Imaging
; 31(8): 1136-45, 2004 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15007564