Detalhe da pesquisa
1.
Targeting the DNA damage response for cancer therapy.
Biochem Soc Trans
; 51(1): 207-221, 2023 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36606678
2.
DNA damage checkpoint kinases in cancer.
Expert Rev Mol Med
; 22: e2, 2020 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32508294
3.
Warburg and Krebs and related effects in cancer.
Expert Rev Mol Med
; 21: e4, 2019 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31558177
4.
PARP inhibitor rucaparib induces changes in NAD levels in cells and liver tissues as assessed by MRS.
NMR Biomed
; 30(9)2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28543772
5.
High-resolution imaging for the detection and characterisation of circulating tumour cells from patients with oesophageal, hepatocellular, thyroid and ovarian cancers.
Int J Cancer
; 138(1): 206-16, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26178530
6.
Imagestream detection and characterisation of circulating tumour cells - A liquid biopsy for hepatocellular carcinoma?
J Hepatol
; 65(2): 305-13, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27132171
7.
Poly(ADP-Ribose) Polymerase in Cervical Cancer Pathogenesis: Mechanism and Potential Role for PARP Inhibitors.
Int J Gynecol Cancer
; 26(4): 763-9, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26905326
8.
Advanced Ovarian Cancer Displays Functional Intratumor Heterogeneity That Correlates to Ex Vivo Drug Sensitivity.
Int J Gynecol Cancer
; 26(6): 1004-11, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27327149
9.
DNA-PK inhibition by NU7441 sensitizes breast cancer cells to ionizing radiation and doxorubicin.
Breast Cancer Res Treat
; 143(1): 47-55, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24292814
10.
Poly(ADP-ribose) polymerase inhibitors in Ewing sarcoma.
Curr Opin Oncol
; 26(4): 428-33, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24840521
11.
Visualization of a DNA-PK/PARP1 complex.
Nucleic Acids Res
; 40(9): 4168-77, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22223246
12.
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.
Breast Cancer Res
; 15(5): R92, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24286369
13.
Poly(ADP-ribose) polymerase-1 (PARP-1) pharmacogenetics, activity and expression analysis in cancer patients and healthy volunteers.
Biochem J
; 436(3): 671-9, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21434873
14.
The Role of ATR Inhibitors in Ovarian Cancer: Investigating Predictive Biomarkers of Response.
Cells
; 11(15)2022 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35954206
15.
Radiotherapy biobanking: current landscape, opportunities, challenges, and future aspirations.
J Pathol Clin Res
; 8(1): 3-13, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34658150
16.
Differences in Durability of PARP Inhibition by Clinically Approved PARP Inhibitors: Implications for Combinations and Scheduling.
Cancers (Basel)
; 14(22)2022 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36428653
17.
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.
Nature
; 434(7035): 913-7, 2005 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-15829966
18.
Genomic, Transcriptomic, and Functional Alterations in DNA Damage Response Pathways as Putative Biomarkers of Chemotherapy Response in Ovarian Cancer.
Cancers (Basel)
; 13(6)2021 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33804647
19.
Increased Replication Stress Determines ATR Inhibitor Sensitivity in Neuroblastoma Cells.
Cancers (Basel)
; 13(24)2021 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34944835
20.
Synthesis and biological evaluation of 5-substituted O4-alkylpyrimidines as CDK2 inhibitors.
Org Biomol Chem
; 8(10): 2397-407, 2010 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20448898