Detalhe da pesquisa
1.
Optimization of 8-oxoadenines with toll-like-receptor 7 and 8 activity.
Bioorg Med Chem Lett
; 30(6): 126984, 2020 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32001135
2.
Novel Lipidated Imidazoquinoline TLR7/8 Adjuvants Elicit Influenza-Specific Th1 Immune Responses and Protect Against Heterologous H3N2 Influenza Challenge in Mice.
Front Immunol
; 11: 406, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32210973
3.
Co-encapsulation of synthetic lipidated TLR4 and TLR7/8 agonists in the liposomal bilayer results in a rapid, synergistic enhancement of vaccine-mediated humoral immunity.
J Control Release
; 315: 186-196, 2019 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31654684
4.
Synthetic Toll-like Receptors 7 and 8 Agonists: Structure-Activity Relationship in the Oxoadenine Series.
ACS Omega
; 4(13): 15665-15677, 2019 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31572869