Detalhe da pesquisa
1.
TET2 Drives 5hmc Marking of GATA6 and Epigenetically Defines Pancreatic Ductal Adenocarcinoma Transcriptional Subtypes.
Gastroenterology
; 161(2): 653-668.e16, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33915173
2.
Development of a potent and selective cell penetrant Legumain inhibitor.
Bioorg Med Chem Lett
; 25(23): 5642-5, 2015 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26522952
3.
BRCA1 is a key regulator of breast differentiation through activation of Notch signalling with implications for anti-endocrine treatment of breast cancers.
Nucleic Acids Res
; 41(18): 8601-14, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23863842
4.
P3 SAR exploration of biphenyl carbamate based Legumain inhibitors.
Bioorg Med Chem Lett
; 24(11): 2521-4, 2014 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24775305
5.
PD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy.
EMBO Mol Med
; 9(2): 167-180, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27932443
6.
Gemcitabine-Induced TIMP1 Attenuates Therapy Response and Promotes Tumor Growth and Liver Metastasis in Pancreatic Cancer.
Cancer Res
; 77(21): 5952-5962, 2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28765154
7.
An efficient and robust MRI-guided radiotherapy planning approach for targeting abdominal organs and tumours in the mouse.
PLoS One
; 12(4): e0176693, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28453537
8.
The identification of a novel role for BRCA1 in regulating RNA polymerase I transcription.
Oncotarget
; 7(42): 68097-68110, 2016 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27589844
9.
The prognostic role of desmoplastic stroma in pancreatic ductal adenocarcinoma.
Oncotarget
; 7(4): 4183-94, 2016 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26716653
10.
Prognostic value, localization and correlation of PD-1/PD-L1, CD8 and FOXP3 with the desmoplastic stroma in pancreatic ductal adenocarcinoma.
Oncotarget
; 7(27): 40992-41004, 2016 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27329602
11.
Prognostic role and correlation of CA9, CD31, CD68 and CD20 with the desmoplastic stroma in pancreatic ductal adenocarcinoma.
Oncotarget
; 7(45): 72819-72832, 2016 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27637082
12.
TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities.
Oncotarget
; 5(6): 1609-20, 2014 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-24742492