Detalhe da pesquisa
1.
An evolutionary conserved detoxification system for membrane lipid-derived peroxyl radicals in Gram-negative bacteria.
PLoS Biol
; 20(5): e3001610, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35580139
2.
Pharmacological chaperones improve intra-domain stability and inter-domain assembly via distinct binding sites to rescue misfolded CFTR.
Cell Mol Life Sci
; 78(23): 7813-7829, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34714360
3.
In Vitro Rescue of the Bile Acid Transport Function of ABCB11 Variants by CFTR Potentiators.
Int J Mol Sci
; 23(18)2022 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36142670
4.
Interest of Homodialkyl Neamine Derivatives against Resistant P. aeruginosa, E. coli, and ß-Lactamases-Producing Bacteria-Effect of Alkyl Chain Length on the Interaction with LPS.
Int J Mol Sci
; 22(16)2021 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34445410
5.
Amphiphilic Aminoglycosides as Medicinal Agents.
Int J Mol Sci
; 21(19)2020 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33049963
6.
A Short Chemically Modified dsRNA-Binding PNA (dbPNA) Inhibits Influenza Viral Replication by Targeting Viral RNA Panhandle Structure.
Bioconjug Chem
; 30(3): 931-943, 2019 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-30721034
7.
Combining theoretical and experimental data to decipher CFTR 3D structures and functions.
Cell Mol Life Sci
; 75(20): 3829-3855, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-29779042
8.
RNA Secondary Structure-Based Design of Antisense Peptide Nucleic Acids for Modulating Disease-Associated Aberrant Tau Pre-mRNA Alternative Splicing.
Molecules
; 24(16)2019 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31434312
9.
Negatively Charged Lipids as a Potential Target for New Amphiphilic Aminoglycoside Antibiotics: A BIOPHYSICAL STUDY.
J Biol Chem
; 291(26): 13864-74, 2016 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27189936
10.
Medicinal chemistry of antischistosomal drugs: Praziquantel and oxamniquine.
Bioorg Med Chem
; 25(13): 3259-3277, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28495384
11.
New amphiphilic neamine derivatives active against resistant Pseudomonas aeruginosa and their interactions with lipopolysaccharides.
Antimicrob Agents Chemother
; 58(8): 4420-30, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24867965
12.
Antibiotic drugs aminoglycosides cleave DNA at abasic sites: shedding new light on their toxicity?
Chem Res Toxicol
; 26(11): 1710-9, 2013 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24127848
13.
The Pseudomonas aeruginosa membranes: a target for a new amphiphilic aminoglycoside derivative?
Biochim Biophys Acta
; 1808(6): 1716-27, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21291859
14.
Synthesis and Evaluation of 2-Aminothiophene Derivatives as Staphylococcus aureus Efflux Pump Inhibitors.
ChemMedChem
; 15(8): 716-725, 2020 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32073756
15.
Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity.
Eur J Med Chem
; 190: 112116, 2020 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32078860
16.
Synthesis and transfection properties of a series of lipidic neamine derivatives.
Bioconjug Chem
; 20(11): 2032-46, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19848402
17.
Enantioseparation by MEKC using a ligand exchange-based chiral pseudostationary phase.
Electrophoresis
; 30(16): 2869-73, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19637217
18.
Chiral ligand-exchange chromatography of amino acids using porous graphitic carbon coated with a dinaphthyl derivative of neamine.
Anal Bioanal Chem
; 393(2): 655-60, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18998115
19.
Antimicrobial activity of amphiphilic neamine derivatives: Understanding the mechanism of action on Gram-positive bacteria.
Biochim Biophys Acta Biomembr
; 1861(10): 182998, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31153908
20.
Copper(II) complexes of lipophilic aminoglycoside derivatives for the amino acid enantiomeric separation by ligand-exchange liquid chromatography.
J Chromatogr A
; 1185(2): 291-5, 2008 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-18295773