Detalhe da pesquisa
1.
Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models.
Prostate
; 2024 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38619005
2.
Third generation quinoline-3-carboxamide transcriptional disrupter of HDAC4, HIF-1α, and MEF-2 signaling for metastatic castration-resistant prostate cancer.
Prostate
; 83(15): 1470-1493, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37559436
3.
Androgen receptor (AR) suppresses normal human prostate epithelial cell proliferation via AR/ß-catenin/TCF-4 complex inhibition of c-MYC transcription.
Prostate
; 74(11): 1118-31, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24913829
4.
Tasquinimod prevents the angiogenic rebound induced by fractionated radiation resulting in an enhanced therapeutic response of prostate cancer xenografts.
Prostate
; 72(6): 638-48, 2012 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21837778
5.
Androgen receptor activity in prostate cancer dictates efficacy of bipolar androgen therapy through MYC.
J Clin Invest
; 132(23)2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36194476
6.
Resistance to androgen receptor signaling inhibition does not necessitate development of neuroendocrine prostate cancer.
JCI Insight
; 6(8)2021 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33724955
7.
Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors.
Oncogene
; 39(45): 6935-6949, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32989253
8.
Microparticle Encapsulation of a Prostate-targeted Biologic for the Treatment of Liver Metastases in a Preclinical Model of Castration-resistant Prostate Cancer.
Mol Cancer Ther
; 19(11): 2353-2362, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32943549
9.
Detection and quantification of the evolution dynamics of apoptosis using the PET voltage sensor 18F-fluorobenzyl triphenyl phosphonium.
J Nucl Med
; 50(5): 774-80, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19372481
10.
Pharmacologic basis for the enhanced efficacy of dutasteride against prostatic cancers.
Clin Cancer Res
; 12(13): 4072-9, 2006 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16818707
11.
Assessing angiogenic responses induced by primary human prostate stromal cells in a three-dimensional fibrin matrix assay.
Oncotarget
; 7(44): 71298-71308, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27542256
12.
Correction: Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors.
Oncogene
; 40(22): 3914-3916, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33958727
13.
Correction to: Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors.
Oncogene
; 40(11): 2148, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33564077
14.
Anti-cancer potency of tasquinimod is enhanced via albumin-binding facilitating increased uptake in the tumor microenvironment.
Oncotarget
; 5(18): 8093-106, 2014 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-25193858
15.
Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment.
Cancer Res
; 73(4): 1386-99, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23149916
16.
Loss of androgen receptor-dependent growth suppression by prostate cancer cells can occur independently from acquiring oncogenic addiction to androgen receptor signaling.
PLoS One
; 5(7): e11475, 2010 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20628607
17.
Amino acid containing thapsigargin analogues deplete androgen receptor protein via synthesis inhibition and induce the death of prostate cancer cells.
Mol Cancer Ther
; 8(5): 1340-9, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19417145
18.
The quinoline-3-carboxamide anti-angiogenic agent, tasquinimod, enhances the anti-prostate cancer efficacy of androgen ablation and taxotere without effecting serum PSA directly in human xenografts.
Prostate
; 67(7): 790-7, 2007 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17373719
19.
PC3, but not DU145, human prostate cancer cells retain the coregulators required for tumor suppressor ability of androgen receptor.
Prostate
; 66(12): 1329-38, 2006 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16835890
20.
Low-calcium serum-free defined medium selects for growth of normal prostatic epithelial stem cells.
Cancer Res
; 66(17): 8598-607, 2006 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16951173