Detalhe da pesquisa
1.
TRACE generates fluorescent human reporter cell lines to characterize epigenetic pathways.
Mol Cell
; 82(2): 479-491.e7, 2022 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34963054
2.
A Polycomb domain found in committed cells impairs differentiation when introduced into PRC1 in pluripotent cells.
Mol Cell
; 81(22): 4677-4691.e8, 2021 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34637753
3.
The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORα/γ.
Genes Dev
; 31(12): 1202-1211, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28747429
4.
Full methylation of H3K27 by PRC2 is dispensable for initial embryoid body formation but required to maintain differentiated cell identity.
Development
; 148(7)2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33688077
5.
HNF6 and Rev-erbα integrate hepatic lipid metabolism by overlapping and distinct transcriptional mechanisms.
Genes Dev
; 30(14): 1636-44, 2016 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27445394
6.
Elongin A associates with actively transcribed genes and modulates enhancer RNA levels with limited impact on transcription elongation rate in vivo.
J Biol Chem
; 296: 100202, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33334895
7.
Identification of C2CD4A as a human diabetes susceptibility gene with a role in ß cell insulin secretion.
Proc Natl Acad Sci U S A
; 116(40): 20033-20042, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31527256
8.
HERVH-derived lncRNAs negatively regulate chromatin targeting and remodeling mediated by CHD7.
Life Sci Alliance
; 5(1)2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34663690
9.
S-phase Enriched Non-coding RNAs Regulate Gene Expression and Cell Cycle Progression.
Cell Rep
; 31(6): 107629, 2020 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32402276
10.
Induction of α cell-restricted Gc in dedifferentiating ß cells contributes to stress-induced ß-cell dysfunction.
JCI Insight
; 52019 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31120862
11.
Integrated omics approaches to characterize a nuclear receptor corepressor-associated histone deacetylase in mouse skeletal muscle.
Mol Cell Endocrinol
; 471: 22-32, 2018 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28554803
12.
Deletion of histone deacetylase 3 in adult beta cells improves glucose tolerance via increased insulin secretion.
Mol Metab
; 6(1): 30-37, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28123935
13.
An HDAC3-PROX1 corepressor module acts on HNF4α to control hepatic triglycerides.
Nat Commun
; 8(1): 549, 2017 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28916805
14.
Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion.
Nat Med
; 23(2): 223-234, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27991918
15.
Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice.
J Clin Invest
; 127(4): 1451-1462, 2017 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28240605
16.
Tumor-associated B-cells induce tumor heterogeneity and therapy resistance.
Nat Commun
; 8(1): 607, 2017 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28928360
17.
Genetic backgrounds determine brown remodeling of white fat in rodents.
Mol Metab
; 5(10): 948-958, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27689007
18.
Physiological Suppression of Lipotoxic Liver Damage by Complementary Actions of HDAC3 and SCAP/SREBP.
Cell Metab
; 24(6): 863-874, 2016 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27866836
19.
GENE REGULATION. Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock.
Science
; 348(6242): 1488-92, 2015 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26044300