Detalhe da pesquisa
1.
Fibroblast growth factor receptor 1/Klothoß agonist BFKB8488A improves lipids and liver health markers in patients with diabetes or NAFLD: A phase 1b randomized trial.
Hepatology
; 78(3): 847-862, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35993161
2.
Dose escalation randomised study of efmarodocokin alfa in healthy volunteers and patients with ulcerative colitis.
Gut
; 72(8): 1451-1461, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-36732049
3.
Phase 2 randomized clinical trial of astegolimab in patients with moderate to severe atopic dermatitis.
J Allergy Clin Immunol
; 150(6): 1517-1524, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36041655
4.
Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trial.
J Allergy Clin Immunol
; 148(3): 790-798, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33872652
5.
Recapitulation of metabolic defects in a model of propionic acidemia using patient-derived primary hepatocytes.
Mol Genet Metab
; 117(3): 355-362, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26740382
6.
Simulation-based evaluation of personalized dosing approaches for anti-FGFR/KLB bispecific antibody fazpilodemab.
CPT Pharmacometrics Syst Pharmacol
; 13(4): 544-550, 2024 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38343040
7.
Optical Microscope Based Universal Parameter for Identifying Layer Number in Two-Dimensional Materials.
ACS Nano
; 16(9): 14456-14462, 2022 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36074897
8.
Consensus Guidelines: Best Practices for Detection, Assessment and Management of Suspected Acute Drug-Induced Liver Injury During Clinical Trials in Adults with Chronic Viral Hepatitis and Adults with Cirrhosis Secondary to Hepatitis B, C and Nonalcoholic Steatohepatitis.
Drug Saf
; 44(2): 133-165, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33141341
9.
Perfused multiwell plate for 3D liver tissue engineering.
Lab Chip
; 10(1): 51-8, 2010 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20024050
10.
Proteins modified by the lipid peroxidation aldehyde 9,12-dioxo-10(E)-dodecenoic acid in MCF7 breast cancer cells.
Chem Res Toxicol
; 23(3): 557-67, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20131800
11.
Next-Generation DILI Biomarkers: Prioritization of Biomarkers for Qualification and Best Practices for Biospecimen Collection in Drug Development.
Clin Pharmacol Ther
; 107(2): 333-346, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31314926
12.
Non-alcoholic fatty liver disease (NAFLD) models in drug discovery.
Expert Opin Drug Discov
; 13(2): 193-205, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29190166
13.
Drug-induced steatohepatitis.
Expert Opin Drug Metab Toxicol
; 13(2): 193-204, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27759439
14.
Systems biology for organotypic cell cultures.
ALTEX
; 34(2): 301-310, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27846345
15.
Transcriptional profiling suggests that Nevirapine and Ritonavir cause drug induced liver injury through distinct mechanisms in primary human hepatocytes.
Chem Biol Interact
; 255: 31-44, 2016 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26626330
16.
Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis.
JCI Insight
; 1(20): e90954, 2016 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27942596
17.
One-Pot Fabrication of RGO-Ag3 VO4 Nanocomposites by in situ Photoreduction using Different Sacrificial Agents: High Selectivity Toward Catechol Synthesis and Photodegradation Ability.
Photochem Photobiol
; 90(1): 57-65, 2014 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24102233
18.
Organotypic systems in drug metabolism and toxicity: challenges and opportunities.
Expert Opin Drug Metab Toxicol
; 8(8): 999-1014, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22632603
19.
Liver tissue engineering in the evaluation of drug safety.
Expert Opin Drug Metab Toxicol
; 5(10): 1159-74, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19637986
20.
Novel three-dimensional organotypic liver bioreactor to directly visualize early events in metastatic progression.
Adv Cancer Res
; 97: 225-46, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17419948