Detalhe da pesquisa
1.
Mechanism of dysfunction of human variants of the IRAK4 kinase and a role for its kinase activity in interleukin-1 receptor signaling.
J Biol Chem
; 293(39): 15208-15220, 2018 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30115681
2.
A recessive founder mutation in regulator of telomere elongation helicase 1, RTEL1, underlies severe immunodeficiency and features of Hoyeraal Hreidarsson syndrome.
PLoS Genet
; 9(8): e1003695, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24009516
3.
IRF5 is a novel regulator of CXCL13 expression in breast cancer that regulates CXCR5(+) B- and T-cell trafficking to tumor-conditioned media.
Immunol Cell Biol
; 93(5): 486-99, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25533286
4.
Cell cycle- and DNA repair pathway-specific effects of apoptosis on tumor suppression.
Proc Natl Acad Sci U S A
; 109(25): 9953-8, 2012 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22670056
5.
Chemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cells.
PLoS Genet
; 8(8): e1002935, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22927831
6.
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.
PLoS Genet
; 8(7): e1002772, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22829774
7.
B cell transcription factors: Potential new therapeutic targets for SLE.
Clin Immunol
; 152(1-2): 140-51, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24674882
8.
Distinct fibroblast functions associated with fibrotic and immune-mediated inflammatory diseases and their implications for therapeutic development.
F1000Res
; 13: 54, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38681509
9.
Frontline Science: AMPK regulates metabolic reprogramming necessary for interferon production in human plasmacytoid dendritic cells.
J Leukoc Biol
; 109(2): 299-308, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32640499
10.
The Interleukin-1 Receptor-Associated Kinase 4 Inhibitor PF-06650833 Blocks Inflammation in Preclinical Models of Rheumatic Disease and in Humans Enrolled in a Randomized Clinical Trial.
Arthritis Rheumatol
; 73(12): 2206-2218, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34423919
11.
Inhibition of IRF5 hyperactivation protects from lupus onset and severity.
J Clin Invest
; 130(12): 6700-6717, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32897883
12.
RNAi Transfection Optimized in Primary Naïve B Cells for the Targeted Analysis of Human Plasma Cell Differentiation.
Front Immunol
; 10: 1652, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31396212
13.
B Cell-Intrinsic Role for IRF5 in TLR9/BCR-Induced Human B Cell Activation, Proliferation, and Plasmablast Differentiation.
Front Immunol
; 8: 1938, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29367853
14.
Specific detection of interferon regulatory factor 5 (IRF5): A case of antibody inequality.
Sci Rep
; 6: 31002, 2016 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27481535
15.
Rad50 is dispensable for the maintenance and viability of postmitotic tissues.
Mol Cell Biol
; 29(2): 483-92, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19001091