Detalhe da pesquisa
1.
The Dual Oxidase Duox2 stabilized with DuoxA2 in an enzymatic complex at the surface of the cell produces extracellular H2O2 able to induce DNA damage in an inducible cellular model.
Exp Cell Res
; 384(1): 111620, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31513783
2.
NADPH oxidase DUOX1 promotes long-term persistence of oxidative stress after an exposure to irradiation.
Proc Natl Acad Sci U S A
; 112(16): 5051-6, 2015 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25848056
3.
The type of DUOX-dependent ROS production is dictated by defined sequences in DUOXA.
Exp Cell Res
; 318(18): 2353-64, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22814254
4.
Severe Autoimmune Thyroiditis in Transgenic NOD.H2h4 Mice Expressing Interleukin-4 in the Thyroid.
Thyroid
; 33(3): 351-364, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36416242
5.
Murine Thyroid IL-4 Expression Worsens Hypothyroidism on Iodine Restriction and Mitigates Graves Disease Development.
Endocrinology
; 163(9)2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35881515
6.
Compound heterozygosity for a novel hemizygous missense mutation and a partial deletion affecting the catalytic core of the H2O2-generating enzyme DUOX2 associated with transient congenital hypothyroidism.
Hum Mutat
; 31(4): E1304-19, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20187165
7.
Inhibition of the thyroid hormonogenic H2O2 production by Duox/DuoxA in zebrafish reveals VAS2870 as a new goitrogenic compound.
Mol Cell Endocrinol
; 500: 110635, 2020 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31678421
8.
Dissecting the Role of Thyrotropin in the DNA Damage Response in Human Thyrocytes after 131I, γ Radiation and H2O2.
J Clin Endocrinol Metab
; 105(3)2020 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31701151
9.
Genomewide location analysis of Candida albicans Upc2p, a regulator of sterol metabolism and azole drug resistance.
Eukaryot Cell
; 7(5): 836-47, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18390649
10.
DUOX Defects and Their Roles in Congenital Hypothyroidism.
Methods Mol Biol
; 1982: 667-693, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31172499
11.
Wide Spectrum of DUOX2 Deficiency: From Life-Threatening Compressive Goiter in Infancy to Lifelong Euthyroidism.
Thyroid
; 29(7): 1018-1022, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31030636
12.
Factors contributing to the resistance of the thyrocyte to hydrogen peroxide.
Mol Cell Endocrinol
; 481: 62-70, 2019 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30476559
13.
Expression, Localization, and Regulation of the Sodium Bicarbonate Cotransporter NBCe1 in the Thyroid.
Thyroid
; 29(2): 290-301, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30526387
14.
Guidelines for the Detection of NADPH Oxidases by Immunoblot and RT-qPCR.
Methods Mol Biol
; 1982: 191-229, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31172474
15.
Missense mutations of dual oxidase 2 (DUOX2) implicated in congenital hypothyroidism have impaired trafficking in cells reconstituted with DUOX2 maturation factor.
Mol Endocrinol
; 21(6): 1408-21, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17374849
16.
Autophagy regulates DUOX1 localization and superoxide production in airway epithelial cells during chronic IL-13 stimulation.
Redox Biol
; 14: 272-284, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28982074
17.
Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult.
J Endocrinol
; 192(3): 615-26, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17332529
18.
Overexpression of Interleukin-4 in the Thyroid of Transgenic Mice Upregulates the Expression of Duox1 and the Anion Transporter Pendrin.
Thyroid
; 26(10): 1499-1512, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27599561
19.
Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signaling.
Antioxid Redox Signal
; 20(17): 2776-93, 2014 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24161126
20.
Thyroid hydrogen peroxide production is enhanced by the Th2 cytokines, IL-4 and IL-13, through increased expression of the dual oxidase 2 and its maturation factor DUOXA2.
Free Radic Biol Med
; 56: 216-25, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23010498