Detalhe da pesquisa
1.
APOE2 Exacerbates TDP-43 Related Toxicity in the Absence of Alzheimer Pathology.
Ann Neurol
; 93(4): 830-843, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36546684
2.
Elevated granulocyte colony stimulating factor (CSF) causes cerebellar deficits and anxiety in a model of CSF-1 receptor related leukodystrophy.
Glia
; 71(3): 775-794, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36433736
3.
APOE4 exacerbates α-synuclein seeding activity and contributes to neurotoxicity in Alzheimer's disease with Lewy body pathology.
Acta Neuropathol
; 143(6): 641-662, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35471463
4.
α-Synuclein filaments from transgenic mouse and human synucleinopathy-containing brains are major seed-competent species.
J Biol Chem
; 295(19): 6652-6664, 2020 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32209651
5.
Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease.
J Biol Chem
; 295(31): 10662-10676, 2020 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32493775
6.
Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples.
J Biol Chem
; 294(44): 16451-16464, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31537646
7.
Novel mutation in MAPT exon 13 (p.N410H) causes corticobasal degeneration.
Acta Neuropathol
; 127(2): 271-82, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24121548
8.
Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons.
Cell Stem Cell
; 31(5): 676-693.e10, 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38626772
9.
Relationships between lewy and tau pathologies in 375 consecutive non-Alzheimer's olfactory bulbs.
Mov Disord
; 33(2): 333-334, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29322556
10.
Comprehensive characterization of human brain-derived extracellular vesicles using multiple isolation methods: Implications for diagnostic and therapeutic applications.
J Extracell Vesicles
; 12(8): e12358, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37563857
11.
Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro.
Nat Commun
; 13(1): 5451, 2022 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36114178
12.
Enrichment of Phosphorylated Tau (Thr181) and Functionally Interacting Molecules in Chronic Traumatic Encephalopathy Brain-derived Extracellular Vesicles.
Aging Dis
; 12(6): 1376-1388, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34527416
13.
A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech.
Nat Commun
; 12(1): 3452, 2021 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34103532
14.
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation.
Sci Transl Med
; 13(622): eabe3947, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34851693
15.
MAPT subhaplotypes in corticobasal degeneration: assessing associations with disease risk, severity of tau pathology, and clinical features.
Acta Neuropathol Commun
; 8(1): 218, 2020 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33287913
16.
Microglial Homeostasis Requires Balanced CSF-1/CSF-2 Receptor Signaling.
Cell Rep
; 30(9): 3004-3019.e5, 2020 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32130903
17.
The neuropathological diagnosis of Alzheimer's disease.
Mol Neurodegener
; 14(1): 32, 2019 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31375134
18.
Coexistence of Progressive Supranuclear Palsy With Pontocerebellar Atrophy and Myotonic Dystrophy Type 1.
J Neuropathol Exp Neurol
; 78(8): 756-762, 2019 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31216016
19.
Association of MAPT Subhaplotypes With Risk of Progressive Supranuclear Palsy and Severity of Tau Pathology.
JAMA Neurol
; 76(6): 710-717, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30882841
20.
FTDP-17 with Pick body-like inclusions associated with a novel tau mutation, p.E372G.
Brain Pathol
; 27(5): 612-626, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27529406