Detalhe da pesquisa
1.
Safety, tolerability, pharmacokinetics, and pharmacodynamics of single-dose antiinterleukin- 18 mAb GSK1070806 in healthy and obese subjects.
Int J Clin Pharmacol Ther
; 52(10): 867-79, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25109413
2.
Neutralizing Antibody Validation Testing and Reporting Harmonization.
AAPS J
; 25(4): 69, 2023 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37421491
3.
Immunogenicity assessment of AAV-based gene therapies: An IQ consortium industry white paper.
Mol Ther Methods Clin Dev
; 26: 471-494, 2022 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36092368
4.
Characterization of the robust humoral immune response to GSK2618960, a humanized anti-IL-7 receptor monoclonal antibody, observed in healthy subjects in a Phase 1 study.
PLoS One
; 16(3): e0249049, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33755713
5.
Toward Reference Intervals of ARSA Activity in the Cerebrospinal Fluid: Implication for the Clinical Practice of Metachromatic Leukodystrophy.
J Appl Lab Med
; 6(2): 354-366, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32910180
6.
Immunogenicity Risk Assessment for PEGylated Therapeutics.
AAPS J
; 22(2): 35, 2020 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31993858
7.
A Study to Investigate the Efficacy and Safety of an Anti-Interleukin-18 Monoclonal Antibody in the Treatment of Type 2 Diabetes Mellitus.
PLoS One
; 11(3): e0150018, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26930607
8.
False-positive immunogenicity responses are caused by CD20+ B cell membrane fragments in an anti-ofatumumab antibody bridging assay.
J Immunol Methods
; 394(1-2): 22-31, 2013 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23639298
9.
Development and validation of a cell-based SEAP reporter assay for the detection of neutralizing antibodies against an anti-IL-13 therapeutic antibody.
J Immunol Methods
; 375(1-2): 258-63, 2012 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-22001556