Detalhe da pesquisa
1.
Unexpected Potency Differences between B-Cell-Activating Factor (BAFF) Antagonist Antibodies against Various Forms of BAFF: Trimer, 60-Mer, and Membrane-Bound.
J Pharmacol Exp Ther
; 359(1): 37-44, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27440419
2.
A G protein-biased ligand at the µ-opioid receptor is potently analgesic with reduced gastrointestinal and respiratory dysfunction compared with morphine.
J Pharmacol Exp Ther
; 344(3): 708-17, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23300227
3.
Biased ligands for better cardiovascular drugs: dissecting G-protein-coupled receptor pharmacology.
Circ Res
; 109(2): 205-16, 2011 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21737816
4.
Quantifying ligand bias at seven-transmembrane receptors.
Mol Pharmacol
; 80(3): 367-77, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21610196
5.
Selectively engaging ß-arrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performance.
J Pharmacol Exp Ther
; 335(3): 572-9, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20801892
6.
Beta-arrestins regulate atherosclerosis and neointimal hyperplasia by controlling smooth muscle cell proliferation and migration.
Circ Res
; 103(1): 70-9, 2008 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-18519945
7.
The Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) K1 protein induces expression of angiogenic and invasion factors.
Cancer Res
; 64(8): 2774-81, 2004 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15087393
8.
Structure-activity relationships and discovery of a G protein biased µ opioid receptor ligand, [(3-methoxythiophen-2-yl)methyl]({2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro-[4.5]decan-9-yl]ethyl})amine (TRV130), for the treatment of acute severe pain.
J Med Chem
; 56(20): 8019-31, 2013 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24063433
9.
beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice.
J Clin Invest
; 119(5): 1312-21, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19349687
10.
Beta-arrestin-mediated signaling regulates protein synthesis.
J Biol Chem
; 283(16): 10611-20, 2008 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-18276584
11.
Beta-arrestins and cell signaling.
Annu Rev Physiol
; 69: 483-510, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17305471
12.
A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling.
Proc Natl Acad Sci U S A
; 104(42): 16657-62, 2007 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-17925438
13.
G protein-coupled receptor kinase and beta-arrestin-mediated desensitization of the angiotensin II type 1A receptor elucidated by diacylglycerol dynamics.
J Biol Chem
; 281(47): 36411-9, 2006 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-17008309
14.
The latency-associated nuclear antigen of rhesus monkey rhadinovirus inhibits viral replication through repression of Orf50/Rta transcriptional activation.
J Virol
; 79(5): 3127-38, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15709032
15.
Whole-genome transcription profiling of rhesus monkey rhadinovirus.
J Virol
; 79(13): 8637-50, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15956606
16.
Kinetics of expression of rhesus monkey rhadinovirus (RRV) and identification and characterization of a polycistronic transcript encoding the RRV Orf50/Rta, RRV R8, and R8.1 genes.
J Virol
; 76(19): 9819-31, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12208960
17.
Transcriptional regulation of the K1 gene product of Kaposi's sarcoma-associated herpesvirus.
J Virol
; 76(24): 12574-83, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12438583
18.
Rhesus monkey rhadinovirus (RRV): construction of a RRV-GFP recombinant virus and development of assays to assess viral replication.
Virology
; 312(1): 122-34, 2003 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-12890626
19.
Comparison of the Rta/Orf50 transactivator proteins of gamma-2-herpesviruses.
J Virol
; 78(10): 5491-9, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15113928