Detalhe da pesquisa
1.
Cell-autonomous expression of the acid hydrolase galactocerebrosidase.
Proc Natl Acad Sci U S A
; 117(16): 9032-9041, 2020 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32253319
2.
Genetic ablation of acid ceramidase in Krabbe disease confirms the psychosine hypothesis and identifies a new therapeutic target.
Proc Natl Acad Sci U S A
; 116(40): 20097-20103, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31527255
3.
Synergistic effects of treating the spinal cord and brain in CLN1 disease.
Proc Natl Acad Sci U S A
; 114(29): E5920-E5929, 2017 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28673981
4.
Histochemical localization of palmitoyl protein thioesterase-1 activity.
Mol Genet Metab
; 117(2): 210-6, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26597320
5.
Expression of Nampt in hippocampal and cortical excitatory neurons is critical for cognitive function.
J Neurosci
; 34(17): 5800-15, 2014 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24760840
6.
An anti-neuroinflammatory that targets dysregulated glia enhances the efficacy of CNS-directed gene therapy in murine infantile neuronal ceroid lipofuscinosis.
J Neurosci
; 34(39): 13077-82, 2014 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25253854
7.
Anti-ApoE antibody given after plaque onset decreases Aß accumulation and improves brain function in a mouse model of Aß amyloidosis.
J Neurosci
; 34(21): 7281-92, 2014 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24849360
8.
Gene therapy ameliorates spontaneous seizures associated with cortical neuron loss in a Cln2R207X mouse model.
J Clin Invest
; 133(12)2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37104037
9.
Effects of chronic cannabidiol in a mouse model of naturally occurring neuroinflammation, neurodegeneration, and spontaneous seizures.
Sci Rep
; 12(1): 11286, 2022 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35789177
10.
Cross-species efficacy of enzyme replacement therapy for CLN1 disease in mice and sheep.
J Clin Invest
; 132(20)2022 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36040802
11.
A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation.
Neuron
; 109(23): 3775-3792.e14, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34614421
12.
Conditional knockout of UBC13 produces disturbances in gait and spontaneous locomotion and exploration in mice.
Sci Rep
; 9(1): 4379, 2019 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30867488
13.
Widespread Expression of a Membrane-Tethered Version of the Soluble Lysosomal Enzyme Palmitoyl Protein Thioesterase-1.
JIMD Rep
; 36: 85-92, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28213849
14.
Comprehensive functional characterization of murine infantile Batten disease including Parkinson-like behavior and dopaminergic markers.
Sci Rep
; 5: 12752, 2015 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26238334
15.
Motivational disturbances and effects of L-dopa administration in neurofibromatosis-1 model mice.
PLoS One
; 8(6): e66024, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23762458
16.
Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration.
J Clin Invest
; 123(12): 5389-400, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24270424
17.
Adrenal steroids uniquely influence sexual motivation behavior in male rats.
Behav Sci (Basel)
; 2(3): 195-206, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25379221
18.
Loss of RBPj in postnatal excitatory neurons does not cause neurodegeneration or memory impairments in aged mice.
PLoS One
; 7(10): e48180, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23110206
19.
Bone Marrow Transplantation Alters the Tremor Phenotype in the Murine Model of Globoid-Cell Leukodystrophy.
J Clin Med
; 1(1): 1-14, 2012 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24013457