Detalhe da pesquisa
1.
Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts.
Nucleic Acids Res
; 50(15): 8418-8430, 2022 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35920332
2.
Delivery of Oligonucleotides to the Liver with GalNAc: From Research to Registered Therapeutic Drug.
Mol Ther
; 28(8): 1759-1771, 2020 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32592692
3.
Next-Generation Peptide Nucleic Acid Chimeras Exhibit High Affinity and Potent Gene Silencing.
Biochemistry
; 58(6): 582-589, 2019 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30520300
4.
Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editing.
Nat Commun
; 9(1): 2641, 2018 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29980686
5.
Locked Nucleic Acid Gapmers and Conjugates Potently Silence ADAM33, an Asthma-Associated Metalloprotease with Nuclear-Localized mRNA.
Mol Ther Nucleic Acids
; 8: 158-168, 2017 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28918018
6.
Single-Stranded Silencing RNAs: Hit Rate and Chemical Modification.
Nucleic Acid Ther
; 26(4): 216-22, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27123752