Detalhe da pesquisa
1.
Discovery of selective TYK2 inhibitors: Design, synthesis, in vitro and in silico studies of promising hits with triazolopyrimidinone scaffold.
Bioorg Chem
; 148: 107430, 2024 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-38728909
2.
Development of EphA2 siRNA-loaded lipid nanoparticles and combination with a small-molecule histone demethylase inhibitor in prostate cancer cells and tumor spheroids.
J Nanobiotechnology
; 19(1): 71, 2021 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33685469
3.
Design, synthesis, and in vitro biological evaluation of novel thiazolopyrimidine derivatives as antileishmanial compounds.
Arch Pharm (Weinheim)
; 353(8): e1900325, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32484266
4.
Oxidative DNA Damage-Mediated Genomic Heterogeneity Is Regulated by NKX3.1 in Prostate Cancer.
Cancer Invest
; 37(2): 113-126, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30836777
5.
Inflammation-mediated abrogation of androgen signaling: an in vitro model of prostate cell inflammation.
Mol Carcinog
; 53(2): 85-97, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22911881
6.
Androgen receptor contributes to repairing DNA damage induced by inflammation and oxidative stress in prostate cancer.
Turk J Biol
; 47(5): 325-335, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38155939
7.
Design, synthesis, in vitro - In vivo biological evaluation of novel thiazolopyrimidine compounds as antileishmanial agent with PTR1 inhibition.
Eur J Med Chem
; 247: 115049, 2023 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36577215
8.
Activation of distinct antiviral T-cell immunity: A comparison of bi- and trispecific T-cell engager antibodies with a chimeric antigen receptor targeting HBV envelope proteins.
Front Immunol
; 13: 1029214, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36405686
9.
NKX3.1 contributes to S phase entry and regulates DNA damage response (DDR) in prostate cancer cell lines.
Biochem Biophys Res Commun
; 414(1): 123-8, 2011 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21945437
10.
Nutlin3a-Loaded Nanoparticles Show Enhanced Apoptotic Activity on Prostate Cancer Cells.
Mol Biotechnol
; 61(7): 489-497, 2019 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-31028604
11.
Cytotoxic Activity of Sesquiterpenoids Isolated from Endemic Ferula tenuissima Hub.-Mor & Pesmen.
Turk J Pharm Sci
; 16(4): 476-480, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-32454752
12.
Cycloartane-type sapogenol derivatives inhibit NFκB activation as chemopreventive strategy for inflammation-induced prostate carcinogenesis.
Steroids
; 135: 9-20, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29678446
13.
Use of Non-steroidal Anti-inflammatory Drugs for Chemoprevention of Inflammation-induced Prostate Cancer.
Turk J Pharm Sci
; 14(3): 274-279, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-32454624
14.
European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).
Redox Biol
; 13: 94-162, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28577489
15.
Automated Cell-Based Quantitation of 8-OHdG Damage.
Methods Mol Biol
; 1516: 299-308, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27044043
16.
Inflammation contributes to NKX3.1 loss and augments DNA damage but does not alter the DNA damage response via increased SIRT1 expression.
J Inflamm (Lond)
; 12: 12, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25705129
17.
The redox biology network in cancer pathophysiology and therapeutics.
Redox Biol
; 5: 347-357, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26122399
18.
TNFα-mediated loss of ß-catenin/E-cadherin association and subsequent increase in cell migration is partially restored by NKX3.1 expression in prostate cells.
PLoS One
; 9(10): e109868, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25360740
19.
HOXB13 contributes to G1/S and G2/M checkpoint controls in prostate.
Mol Cell Endocrinol
; 383(1-2): 38-47, 2014 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24325868
20.
Androgen regulated HN1 leads proteosomal degradation of androgen receptor (AR) and negatively influences AR mediated transactivation in prostate cells.
Mol Cell Endocrinol
; 350(1): 107-17, 2012 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22155408