Detalhe da pesquisa
1.
Antibody-mediated blockade of the IL23 receptor destabilizes intratumoral regulatory T cells and enhances immunotherapy.
Proc Natl Acad Sci U S A
; 119(18): e2200757119, 2022 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35482921
2.
Mutant JAK3 signaling is increased by loss of wild-type JAK3 or by acquisition of secondary JAK3 mutations in T-ALL.
Blood
; 131(4): 421-425, 2018 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29187379
3.
Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors.
Blood
; 128(23): 2642-2654, 2016 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27694322
4.
Distinct Acute Lymphoblastic Leukemia (ALL)-associated Janus Kinase 3 (JAK3) Mutants Exhibit Different Cytokine-Receptor Requirements and JAK Inhibitor Specificities.
J Biol Chem
; 290(48): 29022-34, 2015 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26446793
5.
JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model.
Blood
; 124(20): 3092-100, 2014 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25193870
6.
ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia.
Blood
; 124(25): 3738-47, 2014 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25301704
7.
Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia.
Haematologica
; 100(10): 1301-10, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26206799
8.
B-Cell Infiltrate in the Tumor Microenvironment Is Associated With Improved Survival in Resected Lung Adenocarcinoma.
JTO Clin Res Rep
; 4(7): 100527, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37521368
9.
Tadalafil Enhances Immune Signatures in Response to Neoadjuvant Nivolumab in Resectable Head and Neck Squamous Cell Carcinoma.
Clin Cancer Res
; 28(5): 915-927, 2022 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34911681
10.
Precise reconstruction of the TME using bulk RNA-seq and a machine learning algorithm trained on artificial transcriptomes.
Cancer Cell
; 40(8): 879-894.e16, 2022 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35944503
11.
HOXA9 Cooperates with Activated JAK/STAT Signaling to Drive Leukemia Development.
Cancer Discov
; 8(5): 616-631, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29496663
12.
JAK kinase inhibitors for the treatment of acute lymphoblastic leukemia.
J Hematol Oncol
; 8: 91, 2015 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26208852