Detalhe da pesquisa
1.
Discovery and synthesis of cyclohexenyl derivatives as modulators of CC chemokine receptor 2 activity.
Bioorg Med Chem Lett
; 26(2): 662-666, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26631321
2.
Development of BET Inhibitors as Potential Treatments for Cancer: Optimization of Pharmacokinetic Properties.
ACS Med Chem Lett
; 13(7): 1165-1171, 2022 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35859878
3.
Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug Design.
J Med Chem
; 64(19): 14247-14265, 2021 10 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34543572
4.
From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part I: the discovery of CCR3 antagonist development candidate BMS-639623 with picomolar inhibition potency against eosinophil chemotaxis.
Bioorg Med Chem Lett
; 18(2): 576-85, 2008 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18096386
5.
CCR3 antagonists: a potential new therapy for the treatment of asthma. Discovery and structure-activity relationships.
Bioorg Med Chem Lett
; 12(13): 1785-9, 2002 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-12067561