Detalhe da pesquisa
1.
Machine learning-based phenotypic imaging to characterise the targetable biology of Plasmodium falciparum male gametocytes for the development of transmission-blocking antimalarials.
PLoS Pathog
; 19(10): e1011711, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37801466
2.
The Novel bis-1,2,4-Triazine MIPS-0004373 Demonstrates Rapid and Potent Activity against All Blood Stages of the Malaria Parasite.
Antimicrob Agents Chemother
; 65(11): e0031121, 2021 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34460304
3.
A novel multiple-stage antimalarial agent that inhibits protein synthesis.
Nature
; 522(7556): 315-20, 2015 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26085270
4.
Transmission of Artemisinin-Resistant Malaria Parasites to Mosquitoes under Antimalarial Drug Pressure.
Antimicrob Agents Chemother
; 65(1)2020 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33139275
5.
Allele-Specific Isothermal Amplification Method Using Unmodified Self-Stabilizing Competitive Primers.
Anal Chem
; 90(20): 11972-11980, 2018 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30226760
6.
Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis.
Nature
; 537(7618): 122, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27281209
7.
An essential role of the basal body protein SAS-6 in Plasmodium male gamete development and malaria transmission.
Cell Microbiol
; 17(2): 191-206, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25154861
8.
Imaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation.
Antimicrob Agents Chemother
; 59(6): 3298-305, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25801574
9.
Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans.
Antimicrob Agents Chemother
; 59(2): 950-9, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25421480
10.
Quantitative analysis of Plasmodium ookinete motion in three dimensions suggests a critical role for cell shape in the biomechanics of malaria parasite gliding motility.
Cell Microbiol
; 16(5): 734-50, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24612056
11.
Use of Plasmodium falciparum culture-adapted field isolates for in vitro exflagellation-blocking assay.
Malar J
; 14: 234, 2015 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26040313
12.
Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.
Proc Natl Acad Sci U S A
; 109(21): 8298-303, 2012 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22566611
13.
Changes in metabolic phenotypes of Plasmodium falciparum in vitro cultures during gametocyte development.
Malar J
; 13: 468, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25439984
14.
Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria.
Malar J
; 13: 483, 2014 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25486998
15.
Optimisation-based modelling for explainable lead discovery in malaria.
Artif Intell Med
; 147: 102700, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38184363
16.
Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1.
Nat Commun
; 15(1): 5219, 2024 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38890312
17.
Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs.
Antimicrob Agents Chemother
; 57(7): 3268-74, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23629698
18.
A Pyridyl-Furan Series Developed from the Open Global Health Library Block Red Blood Cell Invasion and Protein Trafficking in Plasmodium falciparum through Potential Inhibition of the Parasite's PI4KIIIB Enzyme.
ACS Infect Dis
; 9(9): 1695-1710, 2023 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37639221
19.
A novel class of sulphonamides potently block malaria transmission by targeting a Plasmodium vacuole membrane protein.
Dis Model Mech
; 16(2)2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36715290
20.
Use of a selective inhibitor to define the chemotherapeutic potential of the plasmodial hexose transporter in different stages of the parasite's life cycle.
Antimicrob Agents Chemother
; 55(6): 2824-30, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21402842