Detalhe da pesquisa
1.
Novel MECP2 gene therapy is effective in a multicenter study using two mouse models of Rett syndrome and is safe in non-human primates.
Mol Ther
; 31(9): 2767-2782, 2023 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37481701
2.
CuATSM effectively ameliorates ALS patient astrocyte-mediated motor neuron toxicity in human in vitro models of amyotrophic lateral sclerosis.
Glia
; 71(2): 350-365, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36213964
3.
PolyGA targets the ER stress-adaptive response by impairing GRP75 function at the MAM in C9ORF72-ALS/FTD.
Acta Neuropathol
; 144(5): 939-966, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36121477
4.
Nitration of Hsp90 on Tyrosine 33 Regulates Mitochondrial Metabolism.
J Biol Chem
; 290(31): 19055-66, 2015 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-26085096
5.
MeCP2 gene therapy ameliorates disease phenotype in mouse model for Pitt Hopkins syndrome.
Neurotherapeutics
; : e00376, 2024 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38876822
6.
Neurotoxic Astrocytes Directly Converted from Sporadic and Familial ALS Patient Fibroblasts Reveal Signature Diversities and miR-146a Theragnostic Potential in Specific Subtypes.
Cells
; 11(7)2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35406750
7.
EphA4 targeting agents protect motor neurons from cell death induced by amyotrophic lateral sclerosis -astrocytes.
iScience
; 25(9): 104877, 2022 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36034213
8.
Mechanisms of IRF2BPL-related disorders and identification of a potential therapeutic strategy.
Cell Rep
; 41(10): 111751, 2022 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36476864
9.
Peroxynitrite nitration of Tyr 56 in Hsp90 induces PC12 cell death through P2X7R-dependent PTEN activation.
Redox Biol
; 50: 102247, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35121403
10.
NMR-Guided Design of Potent and Selective EphA4 Agonistic Ligands.
J Med Chem
; 64(15): 11229-11246, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34293864
11.
In vitro Modeling for Neurological Diseases using Direct Conversion from Fibroblasts to Neuronal Progenitor Cells and Differentiation into Astrocytes.
J Vis Exp
; (172)2021 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34180877
12.
Chronic inhibitory effect of riluzole on trophic factor production.
Exp Neurol
; 271: 301-7, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26071088
13.
Temporal patterns of tyrosine nitration in embryo heart development.
Free Radic Biol Med
; 55: 101-8, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23195686