Detalhe da pesquisa
1.
Discovery of pyrrolo[2,1-f][1,2,4]triazine-based inhibitors of adaptor protein 2-associated kinase 1 for the treatment of pain.
Med Chem Res
; : 1-7, 2023 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37362320
2.
Synthesis of functionalized derivatives of the gamma-secretase modulator BMS-932481 and identification of its major metabolite.
Bioorg Med Chem Lett
; 30(22): 127530, 2020 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32890687
3.
Robust Translation of γ-Secretase Modulator Pharmacology across Preclinical Species and Human Subjects.
J Pharmacol Exp Ther
; 358(1): 125-37, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27189974
4.
Pharmacodynamics of selective inhibition of γ-secretase by avagacestat.
J Pharmacol Exp Ther
; 344(3): 686-95, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23275065
5.
Mechanistic investigation of liver injury induced by BMS-932481, an experimental ɣ-secretase modulator.
Toxicol Sci
; 194(2): 235-245, 2023 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37261863
6.
Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780.
Int J Alzheimers Dis
; 2014: 431858, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25097793