Detalhe da pesquisa
1.
Design, synthesis, and antiproliferative effect of 2,9-bis[4-(pyridinylalkylaminomethyl)phenyl]-1,10-phenanthroline derivatives on human leukemic cells by targeting G-quadruplex.
Arch Pharm (Weinheim)
; 354(8): e2000450, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-33852185
2.
Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5-and hypoxia-dependent upregulation of AXL.
Haematologica
; 104(10): 2017-2027, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30923103
3.
Targeting Tyrosine Kinases in Acute Myeloid Leukemia: Why, Who and How?
Int J Mol Sci
; 20(14)2019 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31336846
4.
Effects of Ultra-Low-Dose Aspirin in Thrombosis and Haemorrhage.
Homeopathy
; 108(3): 158-168, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31005060
5.
Design, Synthesis and Biological Evaluation of New Substituted Diquinolinyl-Pyridine Ligands as Anticancer Agents by Targeting G-Quadruplex.
Molecules
; 23(1)2017 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29301210
6.
A new human mast cell line expressing a functional IgE receptor converts to tumorigenic growth by KIT D816V transfection.
Blood
; 124(1): 111-20, 2014 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24677542
7.
CBL controls a tyrosine kinase network involving AXL, SYK and LYN in nilotinib-resistant chronic myeloid leukaemia.
J Pathol
; 237(1): 14-24, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25965880
8.
New 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinazoline and 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinoline Derivatives: Synthesis and Biological Evaluation as Novel Anticancer Agents by Targeting G-Quadruplex.
Pharmaceuticals (Basel)
; 17(1)2023 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38256866
9.
Basis of a FTIR spectroscopy methodology for automated evaluation of Akt kinase inhibitor on leukemic cell lines used as model.
Anal Bioanal Chem
; 404(6-7): 1733-43, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22850898
10.
Autophagy Targeting and Hematological Mobilization in FLT3-ITD Acute Myeloid Leukemia Decrease Repopulating Capacity and Relapse by Inducing Apoptosis of Committed Leukemic Cells.
Cancers (Basel)
; 14(2)2022 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35053612
11.
Synthesis and evaluation of the antiproliferative activity of novel isoindolo[2,1-a]quinoxaline and indolo[1,2-a]quinoxaline derivatives.
J Enzyme Inhib Med Chem
; 26(5): 657-67, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21250818
12.
Dual Inhibition of FLT3 and AXL by Gilteritinib Overcomes Hematopoietic Niche-Driven Resistance Mechanisms in FLT3-ITD Acute Myeloid Leukemia.
Clin Cancer Res
; 27(21): 6012-6025, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34400415
13.
Synthesis and evaluation of the antiproliferative activity of novel pyrrolo[1,2-a]quinoxaline derivatives, potential inhibitors of Akt kinase. Part II.
J Enzyme Inhib Med Chem
; 25(2): 204-15, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20222763
14.
CD23 mediates antimycobacterial activity of human macrophages.
Infect Immun
; 77(12): 5537-42, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19805542
15.
New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: synthesis, and in vitro antimalarial activity.
Bioorg Med Chem
; 16(20): 9133-44, 2008 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18819813
16.
Synthesis of new pyrrolo[1,2-a]quinoxaline derivatives as potential inhibitors of Akt kinase.
J Enzyme Inhib Med Chem
; 23(5): 648-58, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18821254
17.
Reverse effect of aspirin: is the prothrombotic effect after aspirin discontinuation mediated by cyclooxygenase 2 inhibition?
Pathophysiol Haemost Thromb
; 36(1): 40-4, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-18332613
18.
Modifications produced by selective inhibitors of cyclooxygenase and ultra low dose aspirin on platelet activity in portal hypertension.
World J Gastroenterol
; 13(38): 5065-70, 2007 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-17876871
19.
Synthesis and Antiproliferative Effect of Ethyl 4-[4-(4-Substituted Piperidin-1-yl)]benzylpyrrolo[1,2-a]quinoxalinecarboxylate Derivatives on Human Leukemia Cells.
ChemMedChem
; 12(12): 940-953, 2017 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28218826
20.
Chronic myeloid leukemia progenitor cells require autophagy when leaving hypoxia-induced quiescence.
Oncotarget
; 8(57): 96984-96992, 2017 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29228587