Detalhe da pesquisa
1.
Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.
Cell
; 149(5): 1008-22, 2012 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22579044
2.
Developmentally regulated Shh expression is robust to TAD perturbations.
Development
; 146(19)2019 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31511252
3.
Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response.
EMBO J
; 35(8): 831-44, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26903602
4.
Mapping the Shh long-range regulatory domain.
Development
; 141(20): 3934-43, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25252942
5.
Development of five digits is controlled by a bipartite long-range cis-regulator.
Development
; 141(8): 1715-25, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24715461
6.
Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3.
Nat Struct Mol Biol
; 30(2): 188-199, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36635604
7.
Enhancer-adoption as a mechanism of human developmental disease.
Hum Mutat
; 32(12): 1492-9, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21948517
8.
A Highly Conserved Shh Enhancer Coordinates Hypothalamic and Craniofacial Development.
Front Cell Dev Biol
; 9: 595744, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33869166
9.
Point mutations in a distant sonic hedgehog cis-regulator generate a variable regulatory output responsible for preaxial polydactyly.
Hum Mol Genet
; 17(7): 978-85, 2008 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18156157
10.
The pro-apoptotic K-Ras 4A proto-oncoprotein does not affect tumorigenesis in the ApcMin/+ mouse small intestine.
BMC Gastroenterol
; 8: 24, 2008 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18554389
11.
A universal vector for high-efficiency multi-fragment recombineering of BACs and knock-in constructs.
PLoS One
; 8(4): e62054, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23637962
12.
Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly.
Dev Cell
; 22(2): 459-67, 2012 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22340503
13.
Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin.
Nat Genet
; 42(1): 89-93, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20023660
14.
Mutationally activated K-ras 4A and 4B both mediate lung carcinogenesis.
Exp Cell Res
; 314(5): 1105-14, 2008 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-18062963
15.
Effects on kidney disease, fertility and development in mice inheriting a protein-truncating Denys-Drash syndrome allele (Wt1tmT396).
Transgenic Res
; 17(3): 459-75, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18040647
16.
The K-Ras 4A isoform promotes apoptosis but does not affect either lifespan or spontaneous tumor incidence in aging mice.
Exp Cell Res
; 312(1): 16-26, 2006 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16271715