Detalhe da pesquisa
1.
Shaping down syndrome brain cognitive and molecular changes due to aging using adult animals from the Ts66Yah murine model.
Neurobiol Dis
; 196: 106523, 2024 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38705491
2.
High-Fat Diet Leads to Reduced Protein O-GlcNAcylation and Mitochondrial Defects Promoting the Development of Alzheimer's Disease Signatures.
Int J Mol Sci
; 22(7)2021 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33916835
3.
Broad Kinase Inhibition Mitigates Early Neuronal Dysfunction in Tauopathy.
Int J Mol Sci
; 22(3)2021 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33530349
4.
Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome.
Neurobiol Dis
; 137: 104772, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31987911
5.
Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease.
Neurobiol Dis
; 125: 176-189, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30738142
6.
Shining a light on defective autophagy by proteomics approaches: implications for neurodegenerative illnesses.
Expert Rev Proteomics
; 16(11-12): 951-964, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31709850
7.
Poly-ubiquitin profile in Alzheimer disease brain.
Neurobiol Dis
; 118: 129-141, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30003951
8.
Increased Mammalian Target of Rapamycin Signaling Contributes to the Accumulation of Protein Oxidative Damage in a Mouse Model of Down's Syndrome.
Neurodegener Dis
; 16(1-2): 62-8, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26606243
9.
Elevated risk of type 2 diabetes for development of Alzheimer disease: a key role for oxidative stress in brain.
Biochim Biophys Acta
; 1842(9): 1693-706, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24949886
10.
Neuropathological role of PI3K/Akt/mTOR axis in Down syndrome brain.
Biochim Biophys Acta
; 1842(7): 1144-53, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24735980
11.
Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD.
J Neurochem
; 133(5): 739-49, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25645581
12.
mTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy.
Neurobiol Dis
; 84: 39-49, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25796566
13.
Basal brain oxidative and nitrative stress levels are finely regulated by the interplay between superoxide dismutase 2 and p53.
J Neurosci Res
; 93(11): 1728-39, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26251011
14.
Mass spectrometry and redox proteomics: applications in disease.
Mass Spectrom Rev
; 33(4): 277-301, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24930952
15.
Redox proteomics analysis to decipher the neurobiology of Alzheimer-like neurodegeneration: overlaps in Down's syndrome and Alzheimer's disease brain.
Biochem J
; 463(2): 177-89, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25242166
16.
Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: redox proteomics analysis of human brain.
Biochim Biophys Acta
; 1832(8): 1249-59, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23603808
17.
The Janus face of the heme oxygenase/biliverdin reductase system in Alzheimer disease: it's time for reconciliation.
Neurobiol Dis
; 62: 144-59, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24095978
18.
Redox imbalance and metabolic defects in the context of Alzheimer disease.
FEBS Lett
; 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38472147
19.
Proteomics strategies to analyze HPV-transformed cells: relevance to cervical cancer.
Expert Rev Proteomics
; 10(5): 461-72, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24117203
20.
Intranasal Administration of KYCCSRK Peptide Rescues Brain Insulin Signaling Activation and Reduces Alzheimer's Disease-like Neuropathology in a Mouse Model for Down Syndrome.
Antioxidants (Basel)
; 12(1)2023 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36670973